1 to 10 of 64 literature results

• Synapses: sites of cell recognition, adhesion, and functional specification.

  Synapses are specialized adhesive contacts characteristic of many types of cell-cell interactions involving neurons, immune cells, epithelial cells, a…

  Authors: Soichiro Yamada, W James Nelson

  Source: Annual review of biochemistry. 2007

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• Adaptation of core mechanisms to generate cell polarity.

  Cell polarity is defined as asymmetry in cell shape, protein distributions and cell functions. It is characteristic of single-cell organisms, includin…

  Authors: W James Nelson

  Source: Nature. 2003 Apr 17

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• Cadherins in development: cell adhesion, sorting, and tissue morphogenesis.

  Tissue morphogenesis during development is dependent on activities of the cadherin family of cell-cell adhesion proteins that includes classical cadhe…

  Authors: Jennifer M Halbleib, W James Nelson

  Source: Genes & development. 2006 Dec 1

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• Catenins: playing both sides of the synapse.

  Synapses of the central nervous system (CNS) are specialized cell-cell junctions that mediate intercellular signal transmission from one neuron to ano…

  Authors: Adam V Kwiatkowski, William I Weis, W James Nelson

  Source: Current opinion in cell biology. 2007 Oct

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• APC is a component of an organizing template for cortical microtubule networks.

  A microtubule network on the basal cortex of polarized epithelial cells consists of non-centrosomal microtubules of mixed polarity. Here, we investiga…

  Authors: Amy Reilein, W James Nelson

  Source: Nature cell biology. 2005 May

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• Intercellular adhesion in morphogenesis: molecular and biophysical considerations.

  A major challenge in developmental biology is to understand how cellular processes that result from expression of the genetic program determine the ma…

  Authors: Nicolas Borghi, W James Nelson

  Source: Current topics in developmental biology. 2009

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• Alpha-catenin is a molecular switch that binds E-cadherin-beta-catenin and regulates actin-filament assembly.

  Epithelial cell-cell junctions, organized by adhesion proteins and the underlying actin cytoskeleton, are considered to be stable structures maintaini…

  Authors: Frauke Drees, Sabine Pokutta, Soichiro Yamada, W James Nelson, William I Weis

  Source: Cell. 2005 Dec 2

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• Tube morphogenesis: closure, but many openings remain.

  Epithelial and endothelial tubes form the basic structure of many organs and tissues in the fruit fly Drosophila melanogaster, the nematode Caenorhabd…

  Authors: W James Nelson

  Source: Trends in cell biology. 2003 Dec

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• Deconstructing the cadherin-catenin-actin complex.

  Spatial and functional organization of cells in tissues is determined by cell-cell adhesion, thought to be initiated through trans-interactions betwee…

  Authors: Soichiro Yamada, Sabine Pokutta, Frauke Drees, William I Weis, W James Nelson

  Source: Cell. 2005 Dec 2

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• beta-Catenin is a Nek2 substrate involved in centrosome separation.

  beta-Catenin plays important roles in cell adhesion and gene transcription, and has been shown recently to be essential for the establishment of a bip…

  Authors: Shirin Bahmanyar, Daniel D Kaplan, Jennifer G Deluca, Thomas H Giddings, Eileen T O'Toole, Mark Winey, Edward D Salmon, Patrick J Casey, W James Nelson, Angela I M Barth

  Source: Genes & development. 2008 Jan 1

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