1 to 10 of 26 literature results

• Restoring the association of the T cell receptor with CD8 reverses anergy in human tumor-infiltrating lymphocytes.

  For several days after antigenic stimulation, human cytolytic T lymphocyte (CTL) clones exhibit a decrease in their effector activity and in their bin…

  Authors: Nathalie Demotte, Vincent Stroobant, Pierre J Courtoy, Patrick Van Der Smissen, Didier Colau, Immanuel F Luescher, Claire Hivroz, Julie Nicaise, Jean-Luc Squifflet, Michel Mourad,…

  Source: Immunity. 2008 Mar

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• Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase.

  T lymphocytes undergo proliferation arrest when exposed to tryptophan shortage, which can be provoked by indoleamine 2,3-dioxygenase (IDO), an enzyme …

  Authors: Catherine Uyttenhove, Luc Pilotte, Ivan Théate, Vincent Stroobant, Didier Colau, Nicolas Parmentier, Thierry Boon, Benoît J Van den Eynde

  Source: Nature medicine. 2003 Oct

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• Biochemical characterization of dithiol glutaredoxin 8 from Saccharomyces cerevisiae: the catalytic redox mechanism redux.

  Two dithiol glutaredoxins (Grxs), Grx1 and Grx2, from yeast have been characterized to date. A third putative dithiol glutaredoxin-encoding gene (GRX8…

  Authors: Elisabeth Eckers, Melanie Bien, Vincent Stroobant, Johannes M Herrmann, Marcel Deponte

  Source: Biochemistry. 2009 Feb 17

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• Rational design of indoleamine 2,3-dioxygenase inhibitors.

  Indoleamine 2,3-dioxygenase (IDO) is an important therapeutic target for the treatment of diseases such as cancer that involve pathological immune esc…

  Authors: Ute F Röhrig, Loay Awad, Aurélien Grosdidier, Pierre Larrieu, Vincent Stroobant, Didier Colau, Vincenzo Cerundolo, Andrew J G Simpson, Pierre Vogel, Benoît J Van den Eynde,…

  Source: Journal of medicinal chemistry. 2010 Feb 11

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• Characterization of mammalian sedoheptulokinase and mechanism of formation of erythritol in sedoheptulokinase deficiency.

  Our aim was to identify the product formed by sedoheptulokinase and to understand the mechanism of formation of erythritol in patients with sedoheptul…

  Authors: Tamas Kardon, Vincent Stroobant, Maria Veiga-da-Cunha, Emile Van Schaftingen

  Source: FEBS letters. 2008 Oct 15

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• A mammalian protein homologous to fructosamine-3-kinase is a ketosamine-3-kinase acting on psicosamines and ribulosamines but not on fructosamines.

  Fructosamine-3-kinase (FN3K) is an enzyme that appears to be responsible for the removal of fructosamines from proteins. In this study, we report the …

  Authors: François Collard, Ghislain Delpierre, Vincent Stroobant, Gert Matthijs, Emile Van Schaftingen

  Source: Diabetes. 2003 Dec

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• Determination of the minimal fusion peptide of bovine leukemia virus gp30.

  In this study, we determined the minimal N-terminal fusion peptide of the gp30 of the bovine leukemia virus on the basis of the tilted peptide theory.…

  Authors: Aurélien Lorin, Laurence Lins, Vincent Stroobant, Robert Brasseur, Benoit Charloteaux

  Source: Biochemical and biophysical research communications. 2007 Apr 13

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• Development of an anti-IL-12 p40 auto-vaccine: protection in experimental autoimmune encephalomyelitis at the expense of increased sensitivity to infection.

  IL-12 and IL-23, which share the IL-12 p40 subunit, have been ascribed central roles in many autoimmune disorders. We describe here an anti-IL-12 (alp…

  Authors: Catherine Uyttenhove, Berenice Arendse, Vincent Stroobant, Frank Brombacher, Jacques Van Snick

  Source: European journal of immunology. 2004 Dec

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• Tumor-specific shared antigenic peptides recognized by human T cells.

  The first tumor-specific shared antigens and the cancer-germline genes that code for these antigens were identified with antitumor cytolytic T lymphoc…

  Authors: Pierre Van Der Bruggen, Yi Zhang, Pascal Chaux, Vincent Stroobant, Christophe Panichelli, Erwin S Schultz, Jacques Chapiro, Benoît J Van Den Eynde, Francis Brasseur, Thierry Boon

  Source: Immunological reviews. 2002 Oct

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• Splicing of distant Peptide fragments occurs in the proteasome by transpeptidation and produces the spliced antigenic peptide derived from fibroblast growth factor-5.

  Peptide splicing is a newly described mode of production of antigenic peptides presented by MHC class I molecules, whereby two noncontiguous fragments…

  Authors: Alexandre Dalet, Nathalie Vigneron, Vincent Stroobant, Ken-Ichi Hanada, Benoît J Van den Eynde

  Source: Journal of immunology (Baltimore, Md. : 1950). 2010 Mar 15

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