1 to 10 of 26 literature results

• Ral overactivation in malignant peripheral nerve sheath tumors.

  Ras leads an important signaling pathway that is deregulated in neurofibromatosis type 1 and malignant peripheral nerve sheath tumor (MPNST). In this …

  Authors: Vidya Bodempudi, Farnaz Yamoutpoor, Weihong Pan, Arkadiusz Z Dudek, Tuba Esfandyari, Mark Piedra, Dusica Babovick-Vuksanovic, Richard A Woo, Victor F Mautner, Lan Kluwe,…

  Source: Molecular and cellular biology. 2009 Jul

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• Tumor burden in patients with neurofibromatosis types 1 and 2 and schwannomatosis: determination on whole-body MR images.

  PURPOSE: To develop a three-dimensional (3D) segmentation and computerized volumetry technique for use in the assessment of neurofibromatosis and to a…

  Authors: Wenli Cai, Ara Kassarjian, Miriam A Bredella, Gordon J Harris, Hiroyuki Yoshida, Victor F Mautner, Ralph Wenzel, Scott R Plotkin

  Source: Radiology. 2009 Mar

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• Assessment of benign tumor burden by whole-body MRI in patients with neurofibromatosis 1.

  People with neurofibromatosis 1 (NF1) have multiple benign neurofibromas and a 10% lifetime risk of developing malignant peripheral nerve sheath tumor…

  Authors: Victor-F Mautner, Florence A Asuagbor, Eva Dombi, Carsten Fünsterer, Lan Kluwe, Ralf Wenzel, Brigitte C Widemann, Jan M Friedman

  Source: Neuro-oncology. 2008 Aug

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• EGFR and erbB2 in malignant peripheral nerve sheath tumors and implications for targeted therapy.

  Malignant peripheral nerve sheath tumors (MPNSTs) are sarcomas with poor prognosis and limited treatment options. Evidence for a role of epidermal gro…

  Authors: Nikola Holtkamp, Elke Malzer, Jan Zietsch, Ali Fuat Okuducu, Jana Mucha, Christian Mawrin, Victor-F Mautner, Hans-Ulrich Schildhaus, Andreas von Deimling

  Source: Neuro-oncology. 2008 Dec

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• Differential modulation of malignant peripheral nerve sheath tumor growth by omega-3 and omega-6 fatty acids.

  Neurofibromatosis type 1 (NF1) is a common genetic disorder of the nervous system resulting in neurofibromas and malignant peripheral nerve sheath tum…

  Authors: George A Mashour, Stephanie N Drissel, Silke Frahm, Faris Farassati, Robert L Martuza, Victor-F Mautner, Andrea Kindler-Röhrborn, Andreas Kurtz

  Source: Oncogene. 2005 Mar 31

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• Mutation and expression of PDGFRA and KIT in malignant peripheral nerve sheath tumors, and its implications for imatinib sensitivity.

  Platelet-derived growth factor receptor alpha (PDGFRalpha) and c-Kit are receptor tyrosine kinases. Both are targets of the tyrosine kinase inhibitor …

  Authors: Nikola Holtkamp, Ali Fuat Okuducu, Jana Mucha, Anastasia Afanasieva, Christian Hartmann, Isis Atallah, Lope Estevez-Schwarz, Christian Mawrin, Reinhard E Friedrich, Victor-F Mautner,…

  Source: Carcinogenesis. 2006 Mar

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• Prevalence of neurofibromatosis 1 in German children at elementary school enrollment.

  OBJECTIVE: To determine the prevalence of neurofibromatosis 1 (NF1) among 6-year-old children in Germany. SETTING AND PATIENTS: A total of 152819 chil…

  Authors: Marga Lammert, Jan M Friedman, Lan Kluwe, Victor F Mautner

  Source: Archives of dermatology. 2005 Jan

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• Constitutional NF1 mutations in neurofibromatosis 1 patients with malignant peripheral nerve sheath tumors.

  Neurofibromatosis type 1 (NF1) patients have 10% of lifetime risk for developing malignant peripheral nerve sheath tumors (MPNST), one of the most agg…

  Authors: Lan Kluwe, Reinhard E Friedrich, Matthias Peiper, Jan Friedman, Victor-F Mautner

  Source: Human mutation. 2003 Nov

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• Screening 500 unselected neurofibromatosis 1 patients for deletions of the NF1 gene.

  A total of 500 unselected unrelated neurofibromatosis 1 (NF1) patients were screened for deletions of the NF1 gene. After excluding 67 patients with k…

  Authors: Lan Kluwe, Reiner Siebert, Stefan Gesk, Reinhard E Friedrich, Sigrid Tinschert, Hildegard Kehrer-Sawatzki, Victor-F Mautner

  Source: Human mutation. 2004 Feb

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• NF1 mutations in neurofibromatosis 1 patients with plexiform neurofibromas.

  Neurofibromatosis 1 (NF1) is an autosomal dominant disorder caused by genetic alterations of the NF1 gene on 17q11.2. About 30% of NF1 patients develo…

  Authors: Lan Kluwe, Reinhard E Friedrich, Bruce Korf, Raimund Fahsold, Victor-F Mautner

  Source: Human mutation. 2002 Mar

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