1 to 10 of 14 literature results

• In human endothelial cells rapamycin causes mTORC2 inhibition and impairs cell viability and function.

  AIM: Drug-eluting stents are widely used to prevent restenosis but are associated with late endothelial damage. To understand the basis for this effec…

  Authors: Amelia Barilli, Rossana Visigalli, Roberto Sala, Gian C Gazzola, Alessandro Parolari, Elena Tremoli, Sabrina Bonomini, Alexandra Simon, Ellen I Closs, Valeria Dall'Asta,…

  Source: Cardiovascular research. 2008 Jun 1

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• Thioamido coordination in a thioxo-1,2,4-triazole copper(II) complex enhances nonapoptotic programmed cell death associated with copper accumulation and oxidative stress in human cancer cells.

  The thioamido function of [CuCl2(1H)]Cl (2) (1=4-amino-1,4-dihydro-3-(2-pyridyl)-5-thioxo-1,2,4-triazole), a cytotoxic copper complex, was converted i…

  Authors: Saverio Tardito, Ovidio Bussolati, Monica Maffini, Matteo Tegoni, Marco Giannetto, Valeria Dall'asta, Renata Franchi-Gazzola, Maurizio Lanfranchi, Maria Angela Pellinghelli, Claudio Mucchino,…

  Source: Journal of medicinal chemistry. 2007 Apr 19

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• Alveolar macrophages from normal subjects lack the NOS-related system y+ for arginine transport.

  Systems y+ and y+L represent the main routes for arginine transport in mammalian cells. While system y+ activity is needed for the stimulated NO produ…

  Authors: Bianca Maria Rotoli, Valeria Dall'asta, Amelia Barilli, Raffaele D'Ippolito, Annalisa Tipa, Dario Olivieri, Gian C Gazzola, Ovidio Bussolati

  Source: American journal of respiratory cell and molecular biology. 2007 Jul

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• PKC-dependent stimulation of EAAT3 glutamate transporter does not require the integrity of actin cytoskeleton.

  The activity and the membrane expression of EAAT3 glutamate transporter are stimulated upon PKC activation by phorbol esters in C6 rat glioma cells. T…

  Authors: Massimiliano G Bianchi, Bianca Maria Rotoli, Valeria Dall'Asta, Gian C Gazzola, Rita Gatti, Ovidio Bussolati

  Source: Neurochemistry international. 2006 Apr

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• SNAT2 silencing prevents the osmotic induction of transport system A and hinders cell recovery from hypertonic stress.

  Under hypertonic conditions the induction of SLC38A2/SNAT2 leads to the stimulation of transport system A and to the increase in the cell content of a…

  Authors: Elena Bevilacqua, Ovidio Bussolati, Valeria Dall'Asta, Francesca Gaccioli, Roberto Sala, Gian C Gazzola, Renata Franchi-Gazzola

  Source: FEBS letters. 2005 Jun 20

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• INFgamma stimulates arginine transport through system y+L in human monocytes.

  Freshly isolated human monocytes transport L-arginine mostly through a sodium independent, NEM insensitive pathway inhibited by L-leucine in the prese…

  Authors: Bianca Maria Rotoli, Ovidio Bussolati, Roberto Sala, Amelia Barilli, Enrica Talarico, Gian C Gazzola, Valeria Dall'Asta

  Source: FEBS letters. 2004 Jul 30

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• Arginine transport in human erythroid cells: discrimination of CAT1 and 4F2hc/y+LAT2 roles.

  Since arginine metabolites, such as nitric oxide and polyamines, influence the expression of genes involved in erythroid differentiation, the transpor…

  Authors: Bianca Maria Rotoli, Ellen I Closs, Amelia Barilli, Rossana Visigalli, Alexandra Simon, Alice Habermeier, Nicoletta Bianchi, Roberto Gambari, Gian C Gazzola, Ovidio Bussolati,…

  Source: Pflügers Archiv : European journal of physiology. 2009 Oct

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• Rapamycin stimulates arginine influx through CAT2 transporters in human endothelial cells.

  In endothelial cells Tumor Necrosis Factor-alpha (TNFalpha) stimulates arginine transport through the increased expression of SLC7A2/CAT2 transcripts.…

  Authors: Rossana Visigalli, Amelia Barilli, Ovidio Bussolati, Roberto Sala, Gian C Gazzola, Alessandro Parolari, Elena Tremoli, Alexandra Simon, Ellen I Closs, Valeria Dall'Asta

  Source: Biochimica et biophysica acta. 2007 Jun

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• The transport of cationic amino acids in human airway cells: expression of system y+L activity and transepithelial delivery of NOS inhibitors.

  The transport of arginine has been characterized in human airway Calu-3 cells. As assessed with RT-PCR, Calu-3 cells express the genes for several tra…

  Authors: Bianca Maria Rotoli, Ovidio Bussolati, Roberto Sala, Gian C Gazzola, Valeria Dall'Asta

  Source: The FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2005 May

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• Inhibition of glutamine synthetase triggers apoptosis in asparaginase-resistant cells.

  The resistance to L-asparaginase (ASNase) has been associated to the overexpression of asparagine synthetase (AS), although the role played by other m…

  Authors: Bianca Maria Rotoli, Jacopo Uggeri, Valeria Dall'Asta, Rossana Visigalli, Amelia Barilli, Rita Gatti, Guido Orlandini, Gian C Gazzola, Ovidio Bussolati

  Source: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 2005

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