1 to 10 of 19 literature results

• Human C-reactive protein does not promote atherosclerosis in transgenic rabbits.

  BACKGROUND: Although there is a statistically significant association between modestly raised baseline plasma C-reactive protein (CRP) values and futu…

  Authors: Tomonari Koike, Shuji Kitajima, Ying Yu, Kazutoshi Nishijima, Jifeng Zhang, Yukio Ozaki, Masatoshi Morimoto, Teruo Watanabe, Sucharit Bhakdi, Yujiro Asada,…

  Source: Circulation. 2009 Nov 24

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• Macrophage metalloelastase accelerates the progression of atherosclerosis in transgenic rabbits.

  BACKGROUND: Macrophage metalloelastase (matrix metalloproteinase [MMP]-12) is upregulated in atherosclerotic lesions and aneurysm; thus, increased MMP…

  Authors: Jingyan Liang, Enqi Liu, Ying Yu, Shuji Kitajima, Tomonari Koike, Yingji Jin, Masatoshi Morimoto, Kinta Hatakeyama, Yujiro Asada, Teruo Watanabe,…

  Source: Circulation. 2006 Apr 25

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• Association of increased expression of macrophage elastase (matrix metalloproteinase 12) with rheumatoid arthritis.

  OBJECTIVE: Increased enzymatic activity of matrix metalloproteinases (MMPs) may promote the progression of rheumatoid arthritis (RA). We undertook thi…

  Authors: Mozhen Liu, Huijun Sun, Xiaofei Wang, Tomonari Koike, Hajime Mishima, Kotaro Ikeda, Teruo Watanabe, Naoyuki Ochiai, Jianglin Fan

  Source: Arthritis and rheumatism. 2004 Oct

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• Enhanced aortic atherosclerosis in transgenic Watanabe heritable hyperlipidemic rabbits expressing lipoprotein lipase.

  OBJECTIVE: This study was designed to address the effects of increased lipoprotein lipase (LPL) activity on atherosclerosis in the setting of LDL rece…

  Authors: Tomonari Koike, Jingyan Liang, Xiaofei Wang, Tomonaga Ichikawa, Masashi Shiomi, Huijun Sun, Teruo Watanabe, George Liu, Jianglin Fan

  Source: Cardiovascular research. 2005 Feb 1

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• Lp(a) enhances coronary atherosclerosis in transgenic Watanabe heritable hyperlipidemic rabbits.

  Elevated plasma levels of LDL and lipoprotein (a) [Lp(a)] are associated with an increased risk of atherosclerosis and coronary heart disease. However…

  Authors: Shuji Kitajima, Yingji Jin, Tomonari Koike, Ying Yu, Enqi Liu, Masashi Shiomi, Santica M Marcovina, Masatoshi Morimoto, Teruo Watanabe, Jianglin Fan

  Source: Atherosclerosis. 2007 Aug

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• Macrophage-derived lipoprotein lipase increases aortic atherosclerosis in cholesterol-fed Tg rabbits.

  Lipoprotein lipase (LPL) produced by macrophages is upregulated in the atherosclerotic lesions; however, it is not fully understood whether increased …

  Authors: Tomonaga Ichikawa, Jingyan Liang, Shuji Kitajima, Tomonari Koike, Xiaofei Wang, Huijun Sun, Masatoshi Morimoto, Hisataka Shikama, Teruo Watanabe, Nobuhiro Yamada,…

  Source: Atherosclerosis. 2005 Mar

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• Temporal and quantitative analysis of expression of metalloproteinases (MMPs) and their endogenous inhibitors in atherosclerotic lesions.

  Matrix metalloproteinases (MMPs) play an important role in the pathogenesis of vascular diseases, such as atherosclerosis, plaque rupture and aneurysm…

  Authors: Ying Yu, Tomonari Koike, Shuji Kitajima, Enqi Liu, Masatoshi Morimoto, Masashi Shiomi, Kinta Hatakeyama, Yujiro Asada, Ke-Yong Wang, Yasuyuki Sasaguri,…

  Source: Histology and histopathology. 2008 Dec

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• Macrophage-specific overexpression of human matrix metalloproteinase-12 in transgenic rabbits.

  Increased matrix metalloproteinase-12 (MMP-12) has been implicated in atherosclerosis and many other inflammatory processes. To define MMP-12 function…

  Authors: Jianglin Fan, Xiaofei Wang, Lihua Wu, Shin-Ich Matsumoto, Jingyan Liang, Tomonari Koike, Tomonaga Ichikawa, Huijun Sun, Hisataka Shikama, Yasuyuki Sasaguri,…

  Source: Transgenic research. 2004 Jun

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• A minipig model of high-fat/high-sucrose diet-induced diabetes and atherosclerosis.

  Summary Type 2 diabetes is a major risk factor of the development of atherosclerosis in humans. However, studies examining mechanisms underlying diabe…

  Authors: Shoumin Xi, Weidong Yin, Zongbao Wang, Masataka Kusunoki, Xin Lian, Tomonari Koike, Jianglin Fan, Qiuju Zhang

  Source: International journal of experimental pathology. 2004 Oct

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• Increased expression of lipoprotein lipase in transgenic rabbits does not lead to abnormalities in skeletal and heart muscles.

  Lipoprotein lipase (LPL) plays an important role in plasma lipoprotein metabolism and the uptake of free fatty acid in muscle. Previous studies using …

  Authors: Tomonari Koike, Xiaofei Wang, Hiroyuki Unoki, Jingyan Liang, Tomonaga Ichikawa, Shuji Kitajima, Teruo Watanabe, Jianglin Fan

  Source: Muscle & nerve. 2002 Dec

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