1 to 10 of 30 literature results

• TSLP: an epithelial cell cytokine that regulates T cell differentiation by conditioning dendritic cell maturation.

  Dendritic cells (DCs) are professional antigen-presenting cells that have the ability to sense infection and tissue stress, sample and present antigen…

  Authors: Yong-Jun Liu, Vasilli Soumelis, Norihiko Watanabe, Tomoki Ito, Yui-Hsi Wang, Rene de Waal Malefyt, Miyuki Omori, Baohua Zhou, Steven F Ziegler

  Source: Annual review of immunology. 2007

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• Hassall's corpuscles instruct dendritic cells to induce CD4+CD25+ regulatory T cells in human thymus.

  Hassall's corpuscles-first described in the human thymus over 150 years ago-are groups of epithelial cells within the thymic medulla. The physical nat…

  Authors: Norihiko Watanabe, Yi-Hong Wang, Heung Kyu Lee, Tomoki Ito, Yui-Hsi Wang, Wei Cao, Yong-Jun Liu

  Source: Nature. 2005 Aug 25

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• Two functional subsets of FOXP3+ regulatory T cells in human thymus and periphery.

  Previous studies suggest that thymus produces a homogenous population of natural regulatory T (Treg) cells that express a transcriptional factor FOXP3…

  Authors: Tomoki Ito, Shino Hanabuchi, Yi-Hong Wang, Woong Ryeon Park, Kazuhiko Arima, Laura Bover, F Xiao-Feng Qin, Michel Gilliet, Yong-Jun Liu

  Source: Immunity. 2008 Jun

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• Maintenance and polarization of human TH2 central memory T cells by thymic stromal lymphopoietin-activated dendritic cells.

  The identity of TH2 memory cells and the mechanism regulating their maintenance during allergic inflammation remain elusive. We report that circulated…

  Authors: Yui-Hsi Wang, Tomoki Ito, Yi-Hong Wang, Bernhard Homey, Norihiko Watanabe, Rachel Martin, Christopher J Barnes, Bradley W McIntyre, Michel Gilliet, Rakesh Kumar,…

  Source: Immunity. 2006 Jun

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• Specialization, kinetics, and repertoire of type 1 interferon responses by human plasmacytoid predendritic cells.

  Recent studies suggest plasmacytoid predendritic cells (pDCs) and myeloid dendritic cells (mDCs) have the functional plasticity to produce similar amo…

  Authors: Tomoki Ito, Holger Kanzler, Omar Duramad, Wei Cao, Yong-Jun Liu

  Source: Blood. 2006 Mar 15

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• Human plasmacytoid predendritic cells activate NK cells through glucocorticoid-induced tumor necrosis factor receptor-ligand (GITRL).

  Plasmacytoid dendritic cell precursors (pDCs) are professional type I interferon-producing cells, a critical cell type in regulating innate and adapti…

  Authors: Shino Hanabuchi, Norihiko Watanabe, Yi-Hong Wang, Yui-Hsi Wang, Tomoki Ito, Joanne Shaw, Wei Cao, F Xiao-Feng Qin, Yong-Jun Liu

  Source: Blood. 2006 May 1

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• The role of dendritic cell subsets in 2,4,6-trinitrobenzene sulfonic acid-induced ileitis.

  Dendritic cells (DCs) are widely distributed throughout the lymphoid and nonlymphoid tissues, and are important initiators of acquired immunity and al…

  Authors: Shoichi Hoshino, Muneo Inaba, Hiroshi Iwai, Tomoki Ito, Ming Li, M Eric Gershwin, Kazuichi Okazaki, Susumu Ikehara

  Source: Journal of autoimmunity. 2009 Oct 29

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• Hodgkin's reed-sternberg cell line (KM-H2) promotes a bidirectional differentiation of CD4+CD25+Foxp3+ T cells and CD4+ cytotoxic T lymphocytes from CD4+ naive T cells.

  A recent report revealed that a large population of Hodgkin's lymphoma-infiltrating lymphocytes (HLILs) consisted of regulatory T cells. In this study…

  Authors: Tsutomu Tanijiri, Toshiki Shimizu, Kazutaka Uehira, Takashi Yokoi, Hideki Amuro, Hiroyuki Sugimoto, Yoshitaro Torii, Kenichirou Tajima, Tomoki Ito, Ryuichi Amakawa,…

  Source: Journal of leukocyte biology. 2007 Sep

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• Mycobacterium bovis Bacillus Calmette-Guérin suppresses inflammatory Th2 responses by inducing functional alteration of TSLP-activated dendritic cells.

  Allergic diseases such as atopic dermatitis and asthma develop as a consequence of dysregulated T(h)2 responses. Recently, it has been demonstrated th…

  Authors: Takashi Yokoi, Ryuichi Amakawa, Tsutomu Tanijiri, Hiroyuki Sugimoto, Yoshitaro Torii, Hideki Amuro, Yonsu Son, Kenichirou Tajima, Yong-Jun Liu, Tomoki Ito,…

  Source: International immunology. 2008 Oct

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• Prostaglandin E2 is a negative regulator on human plasmacytoid dendritic cells.

  Prostaglandin E2 (PGE2), a major lipid derived from the metabolism of arachidonic acid, is an environmentally bioactive substance produced by inflamma…

  Authors: Yonsu Son, Tomoki Ito, Yoshio Ozaki, Tsutomu Tanijiri, Takashi Yokoi, Kengo Nakamura, Masashi Takebayashi, Ryuichi Amakawa, Shirou Fukuhara

  Source: Immunology. 2006 Sep

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