1 to 10 of 30 literature results

• Dietary feeding of dibenzoylmethane inhibits prostate cancer in transgenic adenocarcinoma of the mouse prostate model.

  Dibenzoylmethane (DBM), a minor beta-diketone constituent of licorice, has been shown to exhibit antineoplastic effects in prostate cancer cell lines …

  Authors: Tin Oo Khor, Siwang Yu, Avanthika Barve, Xingpei Hao, Jin-Liern Hong, Wen Lin, Barbara Foster, Mou-Tuan Huang, Harold L Newmark, Ah-Ng Kong

  Source: Cancer research. 2009 Sep 1

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• Nrf2-deficient mice have an increased susceptibility to dextran sulfate sodium-induced colitis.

  Inflammatory bowel diseases, chronic inflammatory disorders, have been strongly linked with an increased risk of the development of colorectal cancer.…

  Authors: Tin Oo Khor, Mou-Tuan Huang, Ki Han Kwon, Jefferson Y Chan, Bandaru S Reddy, Ah-Ng Kong

  Source: Cancer research. 2006 Dec 15

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• Inhibition of 7,12-dimethylbenz(a)anthracene-induced skin tumorigenesis in C57BL/6 mice by sulforaphane is mediated by nuclear factor E2-related factor 2.

  Sulforaphane, a dietary isothiocyanate, possesses potent chemopreventive effects through the induction of cellular detoxifying/antioxidant enzymes via…

  Authors: Changjiang Xu, Mou-Tuan Huang, Guoxiang Shen, Xiaoling Yuan, Wen Lin, Tin Oo Khor, Allan H Conney, Ah-Ng Tony Kong

  Source: Cancer research. 2006 Aug 15

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• Synergistic effect of combination of phenethyl isothiocyanate and sulforaphane or curcumin and sulforaphane in the inhibition of inflammation.

  PURPOSE: Accumulating evidence from epidemiologic and clinical studies indicates that chronic inflammatory disorders harbor an increased risk of cance…

  Authors: Ka Lung Cheung, Tin Oo Khor, Ah-Ng Kong

  Source: Pharmaceutical research. 2009 Jan

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• Chemoprevention of familial adenomatous polyposis by natural dietary compounds sulforaphane and dibenzoylmethane alone and in combination in ApcMin/+ mouse.

  Cancer chemopreventive agent sulforaphane (SFN) and dibenzoylmethane (DBM) showed antitumorigenesis effects in several rodent carcinogenesis models. I…

  Authors: Guoxiang Shen, Tin Oo Khor, Rong Hu, Siwang Yu, Sujit Nair, Chi-Tang Ho, Bandaru S Reddy, Mou-Tuan Huang, Harold L Newmark, Ah-Ng Tony Kong

  Source: Cancer research. 2007 Oct 15

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• Prevention of azoxymethane-induced colon cancer by combination of low doses of atorvastatin, aspirin, and celecoxib in F 344 rats.

  Preclinical and clinical studies have provided evidence that aspirin, celecoxib, (cyclooxygenase-2 inhibitor), and statins (3-hydroxy-3-methylglutaryl…

  Authors: Bandaru S Reddy, Chung Xiou Wang, Ah-Ng Kong, Tin Oo Khor, Xi Zheng, Vernon E Steele, Levy Kopelovich, Chinthalapally V Rao

  Source: Cancer research. 2006 Apr 15

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• Combined inhibitory effects of curcumin and phenethyl isothiocyanate on the growth of human PC-3 prostate xenografts in immunodeficient mice.

  Earlier studies using prostate cancer cells in culture showed that phenethyl isothiocyanate (PEITC) and curcumin have significant chemopreventive and …

  Authors: Tin Oo Khor, Young-Sam Keum, Wen Lin, Jung-Hwan Kim, Rong Hu, Guoxiang Shen, Changjiang Xu, Avanthika Gopalakrishnan, Bandaru Reddy, Xi Zheng,…

  Source: Cancer research. 2006 Jan 15

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• Dietary cancer chemopreventive agents - targeting inflammation and Nrf2 signaling pathway.

  Accumulating epidemiological and clinical evidence shows that chronic inflammation plays a critical role in neoplastic transformation and progression.…

  Authors: Tin Oo Khor, Siwang Yu, Ah-Ng Kong

  Source: Planta medica. 2008 Oct

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• Chemoprevention of familial adenomatous polyposis in Apc(Min/+) mice by phenethyl isothiocyanate (PEITC).

  Phenethyl isothiocyanate (PEITC) is an isothiocyanate which is a major constituent of watercress and other cruciferous vegetables. Its chemopreventive…

  Authors: Tin Oo Khor, William Ka Lung Cheung, Auemduan Prawan, Bandaru S Reddy, Ah-Ng Tony Kong

  Source: Molecular carcinogenesis. 2008 May

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• Sulforaphane suppressed LPS-induced inflammation in mouse peritoneal macrophages through Nrf2 dependent pathway.

  Sulforaphane (SFN) is a natural isothiocyanate that is present in cruciferous vegetables such as broccoli and cabbage. Previous studies have shown tha…

  Authors: Wen Lin, Rachel T Wu, Tienyuan Wu, Tin-Oo Khor, Hu Wang, Ah-Ng Kong

  Source: Biochemical pharmacology. 2008 Oct 15

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