1 to 9 of 9 literature results

• Inhibition of cytohesins by SecinH3 leads to hepatic insulin resistance.

  G proteins are an important class of regulatory switches in all living systems. They are activated by guanine nucleotide exchange factors (GEFs), whic…

  Authors: Markus Hafner, Anton Schmitz, Imke Grüne, Seergazhi G Srivatsan, Bianca Paul, Waldemar Kolanus, Thomas Quast, Elisabeth Kremmer, Inga Bauer, Michael Famulok

  Source: Nature. 2006 Dec 14

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• A fundamental role of mAbp1 in neutrophils: impact on beta(2) integrin-mediated phagocytosis and adhesion in vivo.

  The mammalian actin-binding protein 1 (mAbp1, Hip-55, SH3P7) is phosphorylated by the nonreceptor tyrosine kinase Syk that has a fundamental effect fo…

  Authors: Jürgen Schymeinsky, Ronald Gerstl, Ingrid Mannigel, Katy Niedung, David Frommhold, Klaus Panthel, Jürgen Heesemann, Michael Sixt, Thomas Quast, Waldemar Kolanus,…

  Source: Blood. 2009 Nov 5

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• Cytohesin-1 controls the activation of RhoA and modulates integrin-dependent adhesion and migration of dendritic cells.

  Adhesion and motility of mammalian leukocytes are essential requirements for innate and adaptive immune defense mechanisms. We show here that the guan…

  Authors: Thomas Quast, Barbara Tappertzhofen, Cora Schild, Jessica Grell, Niklas Czeloth, Reinhold Förster, Ronen Alon, Line Fraemohs, Katrin Dreck, Christian Weber,…

  Source: Blood. 2009 Jun 4

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• Keratinocytes from APP/APLP2-deficient mice are impaired in proliferation, adhesion and migration in vitro.

  Growing evidence shows that the soluble N-terminal form (sAPPalpha) of the amyloid precursor protein (APP) represents an epidermal growth factor foste…

  Authors: Christina Siemes, Thomas Quast, Christiane Kummer, Sven Wehner, Gregor Kirfel, Ulrike Müller, Volker Herzog

  Source: Experimental cell research. 2006 Jul 1

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• Simultaneous cell death and desquamation of the embryonic diffusion barrier during epidermal development.

  The periderm is an epithelial layer covering the emerging epidermis in early embryogenesis of vertebrates. In the chicken embryo, an additional cellul…

  Authors: Manuela Saathoff, Barbara Blum, Thomas Quast, Gregor Kirfel, Volker Herzog

  Source: Experimental cell research. 2004 Oct 1

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• Expression and potential function of beta-amyloid precursor proteins during cutaneous wound repair.

  sAPP, the secretory domain of the beta-amyloid precursor protein (APP), exerts a growth promoting and motogenic activity on keratinocytes. Here we rep…

  Authors: Christiane Kummer, Sven Wehner, Thomas Quast, Sabine Werner, Volker Herzog

  Source: Experimental cell research. 2002 Nov 1

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• Transfer of T cell surface molecules to dendritic cells upon CD4+ T cell priming involves two distinct mechanisms.

  Activation of CD4(+) T cells by APCs occurs by multiple Ag recognition events including the exchange of costimulatory signals and cytokines. Additiona…

  Authors: Annette Busch, Thomas Quast, Sascha Keller, Waldemar Kolanus, Percy Knolle, Peter Altevogt, Andreas Limmer

  Source: Journal of immunology (Baltimore, Md. : 1950). 2008 Sep 15

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• Normalized proliferation of normal and psoriatic keratinocytes by suppression of sAPPalpha-release.

  The soluble form of the beta-amyloid precursor protein (sAPPalpha) is known to function in the autocrine regulation of epidermal growth and repair. He…

  Authors: Christina Siemes, Thomas Quast, Elisabeth Klein, Thomas Bieber, Nigel M Hooper, Volker Herzog

  Source: The Journal of investigative dermatology. 2004 Sep

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• sAPP as a regulator of dendrite motility and melanin release in epidermal melanocytes and melanoma cells.

  Numerous factors including ultraviolet (UV) radiation and growth factors regulate the specific function of epidermal melanocytes. A recently discovere…

  Authors: Thomas Quast, Sven Wehner, Gregor Kirfel, Klaus Jaeger, Michele De Luca, Volker Herzog

  Source: The FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2003 Sep

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