1 to 10 of 46 literature results

• Zebrafish (Danio rerio) embryos as a model for testing proteratogens.

  Zebrafish embryos have been shown to be a useful model for the detection of direct acting teratogens. This communication presents a protocol for a 3-d…

  Authors: Stefan Weigt, Nicole Huebler, Ruben Strecker, Thomas Braunbeck, Thomas H Broschard

  Source: Toxicology. 2011 Mar 15

  View Full Text

• Zebrafish teratogenicity test with metabolic activation (mDarT): effects of phase I activation of acetaminophen on zebrafish Danio rerio embryos.

  The zebrafish Danio rerio embryo test with metabolic activation (mDarT) was developed to assess the teratogenic effects of proteratogens. In this stud…

  Authors: Stefan Weigt, Nicole Huebler, Thomas Braunbeck, Friedrich von Landenberg, Thomas H Broschard

  Source: Toxicology. 2010 Sep 10

  View Full Text

• Sediment-contact fish embryo toxicity assay with Danio rerio to assess particle-bound pollutants in the Tietê River Basin (São Paulo, Brazil).

  The Tietê River and its tributary Pinheiros River receive a highly complex organic and inorganic pollutants load from sanitary sewage and industrial s…

  Authors: Paula Suares Rocha, Conny Bernecker, Ruben Strecker, Carolina Fiorillo Mariani, Marcelo Luiz Martins Pompêo, Volker Storch, Henner Hollert, Thomas Braunbeck

  Source: Ecotoxicology and environmental safety. 2011 Oct

  View Full Text

• Dechorionation as a tool to improve the fish embryo toxicity test (FET) with the zebrafish (Danio rerio).

  Prior to hatching, the zebrafish embryo is surrounded by an acellular envelope, the chorion. Despite repeated speculations, it could not be clarified …

  Authors: Kirsten Henn, Thomas Braunbeck

  Source: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 2011 Jan

  View Full Text

• Changes in toxicity and dioxin-like activity of sediments from the Tietê River (São Paulo, Brazil).

  Acute cytotoxicity (neutral red assay), AhR-mediated toxicity (CYP P450 1A induction potential-EROD assay) and concentrations of PAHs were recorded in…

  Authors: Paula Suares Rocha, Ehab Azab, Burkhard Schmidt, Volker Storch, Henner Hollert, Thomas Braunbeck

  Source: Ecotoxicology and environmental safety. 2010 May

  View Full Text

• Assessment of fish health status in the Upper Danube River by investigation of ultrastructural alterations in the liver of barbel Barbus barbus.

  Despite intensive efforts and tightened guidelines for improvement of water quality over the last 2 decades, declines of fish populations have been re…

  Authors: Stefanie Grund, Steffen Keiter, Melanie Böttcher, Nadja Seitz, Karl Wurm, Werner Manz, Henner Hollert, Thomas Braunbeck

  Source: Diseases of aquatic organisms. 2010 Feb 17

  View Full Text

• Gene-TEQ-a standardized comparative assessment of effects in the comet assay using genotoxicity equivalents.

  Existing methods for the comparison of genotoxic effects in the comet assay bear considerable disadvantages such as the problem to link information ab…

  Authors: Christopher Faßbender, Thomas Braunbeck, Steffen H Keiter

  Source: Journal of environmental monitoring : JEM. 2012 Mar 23

  View Full Text

• Alterations along the Hypothalamic-Pituitary-Thyroid Axis of the Zebrafish (Danio rerio) after Exposure to Propylthiouracil.

  In the past, various approaches have been developed to detect adverse effects of pollutants on the thyroid of vertebrates, most of these with special …

  Authors: Florian Schmidt, Thomas Braunbeck

  Source: Journal of thyroid research. 2011

  View Free Full Text

• Low-dose effects and biphasic effect profiles: is trenbolone a genotoxicant?

  Over the last years, extensive research has documented endocrine-disrupting activities for a significant number of substances including, among others,…

  Authors: Melanie Boettcher, Thomas Kosmehl, Thomas Braunbeck

  Source: Mutation research. 2011 Aug 16

  View Full Text

• Sediment genotoxicity in the Tietê River (São Paulo, Brazil): in vitro comet assay versus in situ micronucleus assay studies.

  The in vitro comet assay with the permanent fish cell line RTL-W1 and the in situ micronucleus assay using erythrocytes from indigenous tilapia (Oreoc…

  Authors: Paula Suares Rocha, George Luiz Luvizotto, Thomas Kosmehl, Melanie Böttcher, Volker Storch, Thomas Braunbeck, Henner Hollert

  Source: Ecotoxicology and environmental safety. 2009 Oct

  View Full Text