1 to 10 of 43 literature results

• Structure of the parainfluenza virus 5 F protein in its metastable, prefusion conformation.

  Enveloped viruses have evolved complex glycoprotein machinery that drives the fusion of viral and cellular membranes, permitting entry of the viral ge…

  Authors: Hsien-Sheng Yin, Xiaolin Wen, Reay G Paterson, Robert A Lamb, Theodore S Jardetzky

  Source: Nature. 2006 Jan 5

  View Full Text

• Class III viral membrane fusion proteins.

  Accumulating structural studies of viral fusion glycoproteins have revealed unanticipated structural relationships between unrelated virus families an…

  Authors: Marija Backovic, Theodore S Jardetzky

  Source: Current opinion in structural biology. 2009 Apr

  View Full Text

• Structural basis of viral invasion: lessons from paramyxovirus F.

  The structures of glycoproteins that mediate enveloped virus entry into cells have revealed dramatic structural changes that accompany membrane fusion…

  Authors: Robert A Lamb, Theodore S Jardetzky

  Source: Current opinion in structural biology. 2007 Aug

  View Free Full Text

• Conformational flexibility in immunoglobulin E-Fc 3-4 revealed in multiple crystal forms.

  The structure of immunoglobulin E (IgE)-Fc(3-4) has been solved in three new crystal forms, providing 13 snapshots of the Fc conformation and revealin…

  Authors: Beth A Wurzburg, Theodore S Jardetzky

  Source: Journal of molecular biology. 2009 Oct 16

  View Full Text

• Cleavage and secretion of Epstein-Barr virus glycoprotein 42 promote membrane fusion with B lymphocytes.

  Epstein-Barr virus (EBV) membrane glycoprotein 42 (gp42) is required for viral entry into B lymphocytes through binding to human leukocyte antigen (HL…

  Authors: Jessica Sorem, Theodore S Jardetzky, Richard Longnecker

  Source: Journal of virology. 2009 Jul

  View Free Full Text

• Bimolecular complementation of paramyxovirus fusion and hemagglutinin-neuraminidase proteins enhances fusion: implications for the mechanism of fusion triggering.

  For paramyxoviruses, entry requires a receptor-binding protein (hemagglutinin-neuraminidase [HN], H, or G) and a fusion protein (F). Like other class …

  Authors: Sarah A Connolly, George P Leser, Theodore S Jardetzky, Robert A Lamb

  Source: Journal of virology. 2009 Nov

  View Full Text

• The structure of the follistatin:activin complex reveals antagonism of both type I and type II receptor binding.

  TGF-beta ligands stimulate diverse cellular differentiation and growth responses by signaling through type I and II receptors. Ligand antagonists, suc…

  Authors: Thomas B Thompson, Thomas F Lerch, Robert W Cook, Teresa K Woodruff, Theodore S Jardetzky

  Source: Developmental cell. 2005 Oct

  View Full Text

• Virology: a class act.

  Authors: Theodore S Jardetzky, Robert A Lamb

  Source: Nature. 2004 Jan 22

  View Full Text

• Functional analysis of glycoprotein L (gL) from rhesus lymphocryptovirus in Epstein-Barr virus-mediated cell fusion indicates a direct role of gL in gB-induced membrane fusion.

  Glycoprotein L (gL), which complexes with gH, is a conserved herpesvirus protein that is essential for Epstein-Barr virus (EBV) entry into host cells.…

  Authors: Aileen E Plate, Jasmina Smajlović, Theodore S Jardetzky, Richard Longnecker

  Source: Journal of virology. 2009 Aug

  View Free Full Text

• Hydrophobic residues that form putative fusion loops of Epstein-Barr virus glycoprotein B are critical for fusion activity.

  To test the importance of the hydrophobic residues within the putative Epstein-Barr virus (EBV) glycoprotein B (gB) fusion loops in membrane fusion, W…

  Authors: Marija Backovic, Theodore S Jardetzky, Richard Longnecker

  Source: Journal of virology. 2007 Sep

  View Free Full Text