1 to 10 of 11 literature results

• Germline mutation of INI1/SMARCB1 in familial schwannomatosis.

  Patients with schwannomatosis develop multiple schwannomas but no vestibular schwannomas diagnostic of neurofibromatosis type 2. We report an inactiva…

  Authors: Theo J M Hulsebos, Astrid S Plomp, Ruud A Wolterman, Els C Robanus-Maandag, Frank Baas, Pieter Wesseling

  Source: American journal of human genetics. 2007 Apr

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• Amplification and overexpression of genes in 17p11.2 ~ p12 in osteosarcoma.

  We summarize and briefly discuss recent findings with respect to the amplification and overexpression of candidate oncogenes in 17p11.2 ~p12 in high-g…

  Authors: Maaike van Dartel, Theo J M Hulsebos

  Source: Cancer genetics and cytogenetics. 2004 Aug

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• Re: Infrequent SMARCB1/INI1 gene alteration in epithelioid sarcoma: a useful tool in distinguishing epithelioid sarcoma from malignant rhabdoid tumor: Direct evidence of mutational inactivation of SMARCB1/INI1 in epithelioid sarcoma.

  Authors: Uta Flucke, Pieter J Slootweg, Thomas Mentzel, Patrick Pauwels, Theo J M Hulsebos

  Source: Human pathology. 2009 Sep

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• Characterization of PMP22 expression in osteosarcoma.

  The peripheral myelin protein (PMP22) gene is highly expressed in peripheral Schwann cells and encodes an important constituent of the myelin sheath. …

  Authors: Maaike van Dartel, Theo J M Hulsebos

  Source: Cancer genetics and cytogenetics. 2004 Jul 15

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• Genetic profiling of a distant second glioblastoma multiforme after radiotherapy: Recurrence or second primary tumor?

  OBJECT: In nearly all patients with glioblastoma multiforme (GBM) a local recurrence develops within a short period of time. In this paper the authors…

  Authors: Krista A van Nifterik, Paula H M Elkhuizen, Rob J van Andel, Lukas J A Stalpers, Sieger Leenstra, M Vincent M Lafleur, W Peter Vandertop, Ben J Slotman, Theo J M Hulsebos, Peter Sminia

  Source: Journal of neurosurgery. 2006 Nov

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• Overexpression through amplification of genes in chromosome region 17p11.2 approximately p12 in high-grade osteosarcoma.

  Osteosarcomas are malignant tumors of the bone that are characterized by complex genetic changes, including loss and amplification of chromosome regio…

  Authors: Maaike van Dartel, Sandra Redeker, Johannes Bras, Marcel Kool, Theo J M Hulsebos

  Source: Cancer genetics and cytogenetics. 2004 Jul 1

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• Infrequent but high-level amplification of 17p11.2 approximately p12 in human glioma.

  We reported previously the amplification of DNA markers in 17p12 in 3 of 60 high-grade gliomas. To detect additional cases, we screened in total 104 g…

  Authors: Maaike van Dartel, Sieger Leenstra, Dirk Troost, Theo J M Hulsebos

  Source: Cancer genetics and cytogenetics. 2003 Jan 15

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• Differential radiosensitizing potential of temozolomide in MGMT promoter methylated glioblastoma multiforme cell lines.

  PURPOSE: To investigate the radiosensitizing potential of temozolomide (TMZ) for human glioblastoma multiforme (GBM) cell lines using single-dose and …

  Authors: Krista A van Nifterik, Jaap van den Berg, Lukas J A Stalpers, M Vincent M Lafleur, Sieger Leenstra, Ben J Slotman, Theo J M Hulsebos, Peter Sminia

  Source: International journal of radiation oncology, biology, physics. 2007 Nov 15

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• Amplification of 17p11.2 approximately p12, including PMP22, TOP3A, and MAPK7, in high-grade osteosarcoma.

  Amplification of region 17p11.2 approximately p12 has been found in 13%-29% of high-grade osteosarcomas, suggesting the presence of an oncogene or onc…

  Authors: Maaike van Dartel, Peter W A Cornelissen, Sandra Redeker, Maija Tarkkanen, Sakari Knuutila, Pancras C W Hogendoorn, Andries Westerveld, Ingrid Gomes, Johannes Bras, Theo J M Hulsebos

  Source: Cancer genetics and cytogenetics. 2002 Dec

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• Localization of a putative low-penetrance ependymoma susceptibility locus to 22q11 using a chromosome 22 tiling-path genomic microarray.

  Ependymomas frequently display allelic loss of chromosome 22 in the absence of mutations in the known tumor-suppressor genes on chromosome 22, suggest…

  Authors: Anneke C J Ammerlaan, Cecilia de Bustos, Abdelhay Ararou, Patrick G Buckley, Kiran K Mantripragada, Marco J Verstegen, Theo J M Hulsebos, Jan P Dumanski

  Source: Genes, chromosomes & cancer. 2005 Aug

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