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7 literature results
HIF (hypoxia-inducible factor) hydroxylases have been implicated in EPO (erythropoietin) production and erythropoiesis. Here we examined the role of e…
Authors: Timothy S Fisher, Paul D Lira, Jeffrey L Stock, David G Perregaux, William H Brissette, Terence R S Ozolins, Baiyong Li
Source: Biochemical and biophysical research communications. 2009 Oct 30
View Full TextThe HIF (hypoxia inducible factor) hydroxylases EGNL1/PHD2 has been implicated in embryonic development. Here we knocked down EGNL1 in vivo by injecti…
Authors: Terence R S Ozolins, Timothy S Fisher, Diane M Nadeau, Jeffrey L Stock, Anne S Klein, Anthony J Milici, Daniel Morton, Margaret B Wilhelms, William H Brissette, Baiyong Li
Source: Biochemical and biophysical research communications. 2009 Dec 18
View Full TextCyclophosphamide (CPA) is a potent and highly effective chemotherapeutic and immunosuppressive agent that has been marketed for about 50 years. Report…
Authors: Terence R S Ozolins
Source: Birth defects research. Part B, Developmental and reproductive toxicology. 2010 Aug
View Full TextMany teratogens induce oxidative stress, altering redox status and redox signaling; this has led to the suggestion that developmental toxicants act by…
Authors: Terence R S Ozolins, Wafa Harrouk, Tonia Doerksen, Jacquetta M Trasler, Barbara F Hales
Source: Teratology. 2002 Oct
View Full TextCongenital heart defects (CHDs) are the most common birth defects in humans. In addition, cardiac malformations represent the most frequently identifi…
Authors: Andrea D Weston, Terence R S Ozolins, Nigel A Brown
Source: Birth defects research. Part C, Embryo today : reviews. 2006 Dec
View Full TextThe rabbit is used extensively in developmental toxicity testing, yet basic information on rabbit embryo development is lacking. The goals of this stu…
Authors: Edward W Carney, Belen Tornesi, Charles Keller, Heather A Findlay, William S Nowland, Valerie A Marshall, Terence R S Ozolins
Source: Birth defects research. Part B, Developmental and reproductive toxicology. 2007 Jun
View Full TextAcetylsalicylic acid (ASA) is a rat teratogen, and exposures on gestational days (GDs) 9 and 10 induce diaphragm, cardiac, and midline defects. ASA in…
Authors: Randal D Streck, Steven W Kumpf, Terence R S Ozolins, Donald B Stedman
Source: Birth defects research. Part B, Developmental and reproductive toxicology. 2003 Feb
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