1 to 10 of 8,649 literature results

• Signalling through RHEB-1 mediates intermittent fasting-induced longevity in C. elegans.

  Dietary restriction is the most effective and reproducible intervention to extend lifespan in divergent species. In mammals, two regimens of dietary r…

  Authors: Sakiko Honjoh, Takuya Yamamoto, Masaharu Uno, Eisuke Nishida

  Source: Nature. 2009 Feb 5

  View Full Text

• Ripples from neighbouring transcription.

  Transcriptional initiation of each gene is assumed to be independently controlled in mammals. On the other hand, recent large-scale transcriptome anal…

  Authors: Miki Ebisuya, Takuya Yamamoto, May Nakajima, Eisuke Nishida

  Source: Nature cell biology. 2008 Sep

  View Full Text

• Single artificial-atom lasing.

  Solid-state superconducting circuits are versatile systems in which quantum states can be engineered and controlled. Recent progress in this area has …

  Authors: O Astafiev, K Inomata, A O Niskanen, T Yamamoto, Yu A Pashkin, Y Nakamura, J S Tsai

  Source: Nature. 2007 Oct 4

  View Full Text

• Kid-mediated chromosome compaction ensures proper nuclear envelope formation.

  Toward the end of mitosis, neighboring chromosomes gather closely to form a compact cluster. This is important for reassembling the nuclear envelope a…

  Authors: Miho Ohsugi, Kenjiro Adachi, Reiko Horai, Shigeru Kakuta, Katsuko Sudo, Hayato Kotaki, Noriko Tokai-Nishizumi, Hiroshi Sagara, Yoichiro Iwakura, Tadashi Yamamoto

  Source: Cell. 2008 Mar 7

  View Full Text

• The Plk1 target Kizuna stabilizes mitotic centrosomes to ensure spindle bipolarity.

  Formation of a bipolar spindle is essential for faithful chromosome segregation at mitosis. Because centrosomes define spindle poles, defects in centr…

  Authors: Naoki Oshimori, Miho Ohsugi, Tadashi Yamamoto

  Source: Nature cell biology. 2006 Oct

  View Full Text

• Treatment of arthritis with a selective inhibitor of c-Fos/activator protein-1.

  To inhibit arthritis upstream of inflammatory cytokine release and matrix metalloproteinase (MMP) action, we designed de novo a small-molecule inhibit…

  Authors: Yukihiko Aikawa, Kimiko Morimoto, Tetsuya Yamamoto, Hisaaki Chaki, Akira Hashiramoto, Hirokazu Narita, Shuichi Hirono, Shunichi Shiozawa

  Source: Nature biotechnology. 2008 Jul

  View Full Text

• Prediction of pharmacokinetic drug-drug interaction caused by changes in cytochrome P450 activity using in vivo information.

  The aim of the present paper was to present an overview of the current status of the methods used to predict the magnitude of pharmacokinetic drug-dru…

  Authors: Akihiro Hisaka, Yoshiyuki Ohno, Takehito Yamamoto, Hiroshi Suzuki

  Source: Pharmacology & therapeutics. 2010 Feb

  View Full Text

• Experimental extraction of an entangled photon pair from two identically decohered pairs.

  Entanglement is considered to be one of the most important resources in quantum information processing schemes, including teleportation, dense coding …

  Authors: Takashi Yamamoto, Masato Koashi, Sahin Kaya Ozdemir, Nobuyuki Imoto

  Source: Nature. 2003 Jan 23

  View Full Text

• Atomic-scale imaging of individual dopant atoms in a buried interface.

  Determining the atomic structure of internal interfaces in materials and devices is critical to understanding their functional properties. Interfacial…

  Authors: N Shibata, S D Findlay, S Azuma, T Mizoguchi, T Yamamoto, Y Ikuhara

  Source: Nature materials. 2009 Aug

  View Full Text

• Happy end in sight after 70 years of controversy.

  Differential auxin transport from the columella to lateral root cap cells as a result of root gravitropism has recently been shown using a GFP-based a…

  Authors: Kotaro T Yamamoto

  Source: Trends in plant science. 2003 Aug

  View Full Text