1 to 10 of 25 literature results

• Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development.

  Common lymphoid progenitors (CLPs) clonally produce both B- and T-cell lineages, but have little myeloid potential in vivo. However, some studies clai…

  Authors: Matthew A Inlay, Deepta Bhattacharya, Debashis Sahoo, Thomas Serwold, Jun Seita, Holger Karsunky, Sylvia K Plevritis, David L Dill, Irving L Weissman

  Source: Genes & development. 2009 Oct 15

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• A pluripotency signature predicts histologic transformation and influences survival in follicular lymphoma patients.

  Histologic transformation (HT) of follicular lymphoma to diffuse large B-cell lymphoma (DLBCL-t) is associated with accelerated disease course and dra…

  Authors: Andrew J Gentles, Ash A Alizadeh, Su-In Lee, June H Myklebust, Catherine M Shachaf, Babak Shahbaba, Ronald Levy, Daphne Koller, Sylvia K Plevritis

  Source: Blood. 2009 Oct 8

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• Effects of mammography screening under different screening schedules: model estimates of potential benefits and harms.

  BACKGROUND: Despite trials of mammography and widespread use, optimal screening policy is controversial. OBJECTIVE: To evaluate U.S. breast cancer scr…

  Authors: Jeanne S Mandelblatt, Kathleen A Cronin, Stephanie Bailey, Donald A Berry, Harry J de Koning, Gerrit Draisma, Hui Huang, Sandra J Lee, Mark Munsell, Sylvia K Plevritis,…

  Source: Annals of internal medicine. 2009 Nov 17

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• Extracting binary signals from microarray time-course data.

  This article presents a new method for analyzing microarray time courses by identifying genes that undergo abrupt transitions in expression level, and…

  Authors: Debashis Sahoo, David L Dill, Rob Tibshirani, Sylvia K Plevritis

  Source: Nucleic acids research. 2007

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• Genomic and proteomic analysis reveals a threshold level of MYC required for tumor maintenance.

  MYC overexpression has been implicated in the pathogenesis of most types of human cancers. MYC is likely to contribute to tumorigenesis by its effects…

  Authors: Catherine M Shachaf, Andrew J Gentles, Sailaja Elchuri, Debashis Sahoo, Yoav Soen, Orr Sharpe, Omar D Perez, Maria Chang, Dennis Mitchel, William H Robinson,…

  Source: Cancer research. 2008 Jul 1

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• Fast calculation of pairwise mutual information for gene regulatory network reconstruction.

  We present a new software implementation to more efficiently compute the mutual information for all pairs of genes from gene expression microarrays. C…

  Authors: Peng Qiu, Andrew J Gentles, Sylvia K Plevritis

  Source: Computer methods and programs in biomedicine. 2009 May

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• A natural history model of stage progression applied to breast cancer.

  Invasive breast cancer is commonly staged as local, regional or distant disease. We present a stochastic model of the natural history of invasive brea…

  Authors: Sylvia K Plevritis, Peter Salzman, Bronislava M Sigal, Peter W Glynn

  Source: Statistics in medicine. 2007 Feb 10

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• Simultaneous class discovery and classification of microarray data using spectral analysis.

  Classification methods are commonly divided into two categories: unsupervised and supervised. Unsupervised methods have the ability to discover new cl…

  Authors: Peng Qiu, Sylvia K Plevritis

  Source: Journal of computational biology : a journal of computational molecular cell biology. 2009 Jul

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• Simulation-based parameter estimation for complex models: a breast cancer natural history modelling illustration.

  Simulation-based parameter estimation offers a powerful means of estimating parameters in complex stochastic models. We illustrate the application of …

  Authors: Yen Lin Chia, Peter Salzman, Sylvia K Plevritis, Peter W Glynn

  Source: Statistical methods in medical research. 2004 Dec

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• Breast magnetic resonance image screening and ductal lavage in women at high genetic risk for breast carcinoma.

  BACKGROUND: Intensive screening is an alternative to prophylactic mastectomy in women at high risk for developing breast carcinoma. The current articl…

  Authors: Anne-Renee Hartman, Bruce L Daniel, Allison W Kurian, Meredith A Mills, Kent W Nowels, Frederick M Dirbas, Kerry E Kingham, Nicki M Chun, Robert J Herfkens, James M Ford,…

  Source: Cancer. 2004 Feb 1

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