1 to 10 of 43 literature results

• HLA-C cell surface expression and control of HIV/AIDS correlate with a variant upstream of HLA-C.

  A variant 35 kb upstream of the HLA-C gene (-35C/T) was previously shown to associate with HLA-C mRNA expression level and steady-state plasma HIV RNA…

  Authors: Rasmi Thomas, Richard Apps, Ying Qi, Xiaojiang Gao, Victoria Male, Colm O'hUigin, Geraldine O'Connor, Dongliang Ge, Jacques Fellay, Jeffrey N Martin,…

  Source: Nature genetics. 2009 Dec

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• AIDS restriction HLA allotypes target distinct intervals of HIV-1 pathogenesis.

  An effective acquired immune response to infectious agents mediated by HLA-restricted T-cell recognition can target different stages of disease pathog…

  Authors: Xiaojiang Gao, Arman Bashirova, Astrid K N Iversen, John Phair, James J Goedert, Susan Buchbinder, Keith Hoots, David Vlahov, Marcus Altfeld, Stephen J O'Brien,…

  Source: Nature medicine. 2005 Dec

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• Effect of aciclovir on HIV-1 acquisition in herpes simplex virus 2 seropositive women and men who have sex with men: a randomised, double-blind, placebo-controlled trial.

  BACKGROUND: Across many observational studies, herpes simplex virus type 2 (HSV-2) infection is associated with two-fold to three-fold increased risk …

  Authors: Connie Celum, Anna Wald, James Hughes, Jorge Sanchez, Stewart Reid, Sinead Delany-Moretlwe, Frances Cowan, Martin Casapia, Abner Ortiz, Jonathan Fuchs,…

  Source: Lancet. 2008 Jun 21

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• Innate partnership of HLA-B and KIR3DL1 subtypes against HIV-1.

  Allotypes of the natural killer (NK) cell receptor KIR3DL1 vary in both NK cell expression patterns and inhibitory capacity upon binding to their liga…

  Authors: Maureen P Martin, Ying Qi, Xiaojiang Gao, Eriko Yamada, Jeffrey N Martin, Florencia Pereyra, Sara Colombo, Elizabeth E Brown, W Lesley Shupert, John Phair,…

  Source: Nature genetics. 2007 Jun

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• Genetic variation in the CCL18-CCL3-CCL4 chemokine gene cluster influences HIV Type 1 transmission and AIDS disease progression.

  CCL3 (MIP-1 alpha), CCL4 (MIP-1 beta), and CCL18 (DC-CK1/PARC/AMAC-1) are potent chemoattractants produced by macrophages, natural killer cells, fibro…

  Authors: William S Modi, James Lautenberger, Ping An, Kevin Scott, James J Goedert, Gregory D Kirk, Susan Buchbinder, John Phair, Sharyne Donfield, Stephen J O'Brien,…

  Source: American journal of human genetics. 2006 Jul

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• Epistatic interaction between KIR3DS1 and HLA-B delays the progression to AIDS.

  Natural killer (NK) cells provide defense in the early stages of the innate immune response against viral infections by producing cytokines and causin…

  Authors: Maureen P Martin, Xiaojiang Gao, Jeong-Hee Lee, George W Nelson, Roger Detels, James J Goedert, Susan Buchbinder, Keith Hoots, David Vlahov, John Trowsdale,…

  Source: Nature genetics. 2002 Aug

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• Age-related prevalence of anal cancer precursors in homosexual men: the EXPLORE study.

  BACKGROUND: Infection with human papillomavirus (HPV) is causally linked to the development of anal and cervical cancer. In the United States, the inc…

  Authors: Peter V Chin-Hong, Eric Vittinghoff, Ross D Cranston, Lynette Browne, Susan Buchbinder, Grant Colfax, Maria Da Costa, Teresa Darragh, Dana Jones Benet, Franklyn Judson,…

  Source: Journal of the National Cancer Institute. 2005 Jun 15

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• The epidemiology of new HIV infections and interventions to limit HIV transmission.

  After the disappointing news reported at the 2008 (15th) Conference on Retroviruses and Opportunistic Infections regarding HIV vaccines, microbicides,…

  Authors: Susan Buchbinder

  Source: Topics in HIV medicine : a publication of the International AIDS Society, USA. 2009 Apr-May

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• Human immunodeficiency virus type 1 (HIV-1) diversity at time of infection is not restricted to certain risk groups or specific HIV-1 subtypes.

  African women frequently acquire several genetically distinct human immunodeficiency virus type 1 (HIV-1) variants from a heterosexual partner, wherea…

  Authors: Manish Sagar, Erin Kirkegaard, E Michelle Long, Connie Celum, Susan Buchbinder, Eric S Daar, Julie Overbaugh

  Source: Journal of virology. 2004 Jul

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• Highlights of the 15th Conference on Retroviruses and Opportunistic Infections. HIV testing and prevention strategies.

  A number of presentations at the 15th Conference on Retroviruses and Opportunistic Infections focused on approaches to identify HIV-infected persons f…

  Authors: Susan Buchbinder

  Source: Topics in HIV medicine : a publication of the International AIDS Society, USA. 2008 Apr-May

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