1 to 10 of 44 literature results

• Nuclear cytokine-activated IKKalpha controls prostate cancer metastasis by repressing Maspin.

  Inflammation enhances tumour promotion through NF-kappaB-dependent mechanisms. NF-kappaB was also proposed to promote metastatogenesis through epithel…

  Authors: Jun-Li Luo, Wei Tan, Jill M Ricono, Olexandr Korchynskyi, Ming Zhang, Steven L Gonias, David A Cheresh, Michael Karin

  Source: Nature. 2007 Apr 5

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• Urokinase: the identity crisis continues.

  Authors: Steven L Gonias

  Source: Blood. 2008 Jul 1

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• Regulation of tumor necrosis factor receptor-1 and the IKK-NF-kappaB pathway by LDL receptor-related protein explains the antiinflammatory activity of this receptor.

  Low-density lipoprotein receptor-related protein (LRP-1) functions in endocytosis and in cell signaling directly (by binding signaling adaptor protein…

  Authors: Alban Gaultier, Sanja Arandjelovic, Sherry Niessen, Cheryl D Overton, MacRae F Linton, Sergio Fazio, W Marie Campana, Benjamin F Cravatt, Steven L Gonias

  Source: Blood. 2008 Jun 1

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• The low-density lipoprotein receptor-related protein regulates cancer cell survival and metastasis development.

  Low-density lipoprotein receptor-related protein-1 (LRP-1) is a multifunctional receptor involved in receptor-mediated endocytosis and cell signaling.…

  Authors: Valérie Montel, Alban Gaultier, Robin D Lester, W Marie Campana, Steven L Gonias

  Source: Cancer research. 2007 Oct 15

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• Low-density lipoprotein receptor-related protein 1 is an essential receptor for myelin phagocytosis.

  Multiple sclerosis (MS) is an autoimmune disease in which myelin is progressively degraded. Because degraded myelin may both initiate and accelerate d…

  Authors: Alban Gaultier, Xiaohua Wu, Natacha Le Moan, Shinako Takimoto, Gatambwa Mukandala, Katerina Akassoglou, W Marie Campana, Steven L Gonias

  Source: Journal of cell science. 2009 Apr 15

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• Schwann cells express erythropoietin receptor and represent a major target for Epo in peripheral nerve injury.

  Erythropoietin (Epo) expresses potent neuroprotective activity in the peripheral nervous system; however, the underlying mechanism remains incompletel…

  Authors: Xiaoqing Li, Steven L Gonias, W Marie Campana

  Source: Glia. 2005 Sep

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• A chemically modified preparation of alpha2-macroglobulin binds beta-amyloid peptide with increased affinity and inhibits Abeta cytotoxicity.

  Macromolecules that bind beta-amyloid peptide (Abeta) and neutralize Abeta cytotoxicity offer a promising new approach for treating Alzheimer's diseas…

  Authors: Joseph M Mettenburg, Sanja Arandjelovic, Steven L Gonias

  Source: Journal of neurochemistry. 2005 Apr

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• A derivative of the plasma protease inhibitor alpha(2)-macroglobulin regulates the response to peripheral nerve injury.

  Peripheral nerve injury induces endoneural inflammation, controlled by diverse cytokines and extracellular mediators. Although inflammation is coupled…

  Authors: Sanja Arandjelovic, Nikola Dragojlovic, Xiaoqing Li, Robert R Myers, W Marie Campana, Steven L Gonias

  Source: Journal of neurochemistry. 2007 Oct

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• The low-density lipoprotein receptor-related protein-1 associates transiently with lipid rafts.

  The low-density lipoprotein receptor-related protein-1 (LRP-1) is a multifunctional receptor that undergoes constitutive endocytosis and recycling. To…

  Authors: Lihua Wu, Steven L Gonias

  Source: Journal of cellular biochemistry. 2005 Dec 1

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• Low density lipoprotein receptor-related protein: regulation of the plasma membrane proteome.

  Proteins in the plasma membrane anchor the cell within its microenvironment and sense changes occurring outside the cell. The anchoring interactions a…

  Authors: Steven L Gonias, Lihua Wu, Ana Maria Salicioni

  Source: Thrombosis and haemostasis. 2004 Jun

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