1 to 4 of 4 literature results

• A unique autophosphorylation site on Tie2/Tek mediates Dok-R phosphotyrosine binding domain binding and function.

  Tie2/Tek is an endothelial cell receptor tyrosine kinase that induces signal transduction pathways involved in cell migration upon angiopoietin-1 (Ang…

  Authors: Nina Jones, Stephen H Chen, Celina Sturk, Zubin Master, Jennifer Tran, Robert S Kerbel, Daniel J Dumont

  Source: Molecular and cellular biology. 2003 Apr

  View Free Full Text

• Differential response of lymphatic, venous and arterial endothelial cells to angiopoietin-1 and angiopoietin-2.

  BACKGROUND: The lymphatic system complements the blood circulatory system in absorption and transport of nutrients, and in the maintenance of homeosta…

  Authors: Vicky P K H Nguyen, Stephen H Chen, Jason Trinh, Harold Kim, Brenda L Coomber, Daniel J Dumont

  Source: BMC cell biology. 2007

  View Full Text

• Gene expression analysis of Tek/Tie2 signaling.

  The elaboration of the vasculature during embryonic development involves restructuring of the early vessels into a more complex vascular network. Of p…

  Authors: Stephen H Chen, Yael Babichev, Natalie Rodrigues, Daniel Voskas, Ling Ling, Vicky P K H Nguyen, Daniel J Dumont

  Source: Physiological genomics. 2005 Jul 14

  View Full Text

• Dok-R binds c-Abl and regulates Abl kinase activity and mediates cytoskeletal reorganization.

  Dok-R, also known as Dok-2/FRIP, belongs to the DOK family of signaling molecules that become tyrosine-phosphorylated by several different receptor an…

  Authors: Zubin Master, Jennifer Tran, Aseem Bishnoi, Stephen H Chen, John M L Ebos, Paul Van Slyke, Robert S Kerbel, Daniel J Dumont

  Source: The Journal of biological chemistry. 2003 Aug 8

  View Full Text