1 to 10 of 45 literature results

• Environment, lifestyle and infertility--an inter-generational issue.

  The effects of adult lifestyle--primarily smoking and diet in women, and sedentary habits generally--are important factors affecting the fertility of …

  Authors: Richard M Sharpe, Stephen Franks

  Source: Nature cell biology. 2002 Oct

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• Candidate genes in women with polycystic ovary syndrome.

  There is plentiful evidence that genetic factors have an important part to play in the etiology of polycystic ovary syndrome. As yet, however, none of…

  Authors: Stephen Franks

  Source: Fertility and sterility. 2006 Jul

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• Follicle dynamics and anovulation in polycystic ovary syndrome.

  BACKGROUND: Polycystic ovary syndrome (PCOS) is the commonest cause of anovulatory infertility and menstrual cycle abnormalities, but the factors resp…

  Authors: Stephen Franks, Jaroslav Stark, Kate Hardy

  Source: Human reproduction update. 2008 Jul-Aug

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• Do animal models of polycystic ovary syndrome help to understand its pathogenesis and management? Yes, but their limitations should be recognized.

  Authors: Stephen Franks

  Source: Endocrinology. 2009 Sep

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• Effect of cell shape and packing density on granulosa cell proliferation and formation of multiple layers during early follicle development in the ovary.

  The postnatal mouse ovary is rich in quiescent and early-growing oocytes, each one surrounded by a layer of somatic granulosa cells (GCs) on a basal l…

  Authors: Patricia Da Silva-Buttkus, Gayani S Jayasooriya, Jocelyn M Mora, Margaret Mobberley, Timothy A Ryder, Marianne Baithun, Jaroslav Stark, Stephen Franks, Kate Hardy

  Source: Journal of cell science. 2008 Dec 1

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• Metabolic characteristics of women with polycystic ovaries and oligo-amenorrhoea but normal androgen levels: implications for the management of polycystic ovary syndrome.

  OBJECTIVE: Application of the newly introduced Rotterdam criteria for polycystic ovary syndrome (PCOS) generates four phenotypic subgroups, defined by…

  Authors: Thomas M Barber, John A H Wass, Mark I McCarthy, Stephen Franks

  Source: Clinical endocrinology. 2007 Apr

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• Assessment and management of anovulatory infertility in polycystic ovary syndrome.

  PCOS is the most common cause of anovulatory infertility. Anovulation in PCOS is exacerbated by weight gain and improved by calorie restriction in ove…

  Authors: Stephen Franks

  Source: Endocrinology and metabolism clinics of North America. 2003 Sep

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• Severe endothelial dysfunction in young women with polycystic ovary syndrome is only partially explained by known cardiovascular risk factors.

  OBJECTIVE: We aimed to assess whether metabolic abnormalities can explain endothelial dysfunction and associated cardiovascular disease risk (CVDr) in…

  Authors: Morten B Sorensen, Stephen Franks, Carole Robertson, Dudley J Pennell, Peter Collins

  Source: Clinical endocrinology. 2006 Nov

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• Development of polycystic ovary syndrome: involvement of genetic and environmental factors.

  We have recently proposed that polycystic ovary syndrome (PCOS) has its origin in fetal life. This hypothesis is based on data from animal models (rhe…

  Authors: Stephen Franks, Mark I McCarthy, Kate Hardy

  Source: International journal of andrology. 2006 Feb

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• Follicle-stimulating hormone affects metaphase I chromosome alignment and increases aneuploidy in mouse oocytes matured in vitro.

  Follicle-Stimulating Hormone (FSH) at a wide range of doses is routinely added to culture media during in vitro maturation (IVM) of oocytes, but the e…

  Authors: Ruth Roberts, Aikaterini Iatropoulou, Daniel Ciantar, Jaroslav Stark, David L Becker, Stephen Franks, Kate Hardy

  Source: Biology of reproduction. 2005 Jan

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