1 to 7 of 7 literature results

• SRC-1 and TIF2 control energy balance between white and brown adipose tissues.

  We have explored the effects of two members of the p160 coregulator family on energy homeostasis. TIF2-/- mice are protected against obesity and displ…

  Authors: Frédéric Picard, Martine Géhin, Jean- Sébastien Annicotte, Stéphane Rocchi, Marie-France Champy, Bert W O'Malley, Pierre Chambon, Johan Auwerx

  Source: Cell. 2002 Dec 27

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• Spleen tyrosine kinase functions as a tumor suppressor in melanoma cells by inducing senescence-like growth arrest.

  Loss of tumor-suppressive pathways that control cellular senescence is a crucial step in malignant transformation. Spleen tyrosine kinase (Syk) is a c…

  Authors: Olivier Bailet, Nina Fenouille, Patricia Abbe, Guillaume Robert, Stéphane Rocchi, Nadège Gonthier, Christophe Denoyelle, Michel Ticchioni, Jean-Paul Ortonne, Robert Ballotti,…

  Source: Cancer research. 2009 Apr 1

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• A short series of antidiabetic sulfonylureas exhibit multiple ligand PPARgamma-binding patterns.

  The present work explores the PPARgamma-activating properties of a series of eight sulfonylureas, using transfection experiments with 293T cells, and …

  Authors: Alban Arrault, Stéphane Rocchi, Frédéric Picard, Pierre Maurois, Bernard Pirotte, Joseph Vamecq

  Source: Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie. 2009 Jan

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• The PPARgamma agonist FMOC-L-leucine protects both mature and immature brain.

  N-[9-fluorenylmethoxycarbonyl]-)-L-leucine (FMOC-L-leucine) and rosiglitazone, two ligands of peroxisome proliferator-activated receptor gamma (PPARga…

  Authors: Pierre Maurois, Stéphane Rocchi, Nicole Pages, Pierre Bac, James P Stables, Pierre Gressens, Joseph Vamecq

  Source: Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie. 2008 Apr-May

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• Transcription factors and nuclear receptors interact with the SWI/SNF complex through the BAF60c subunit.

  Transcriptional activity relies on coregulators that modify chromatin structure or serve as bridging factors between transcription factors and the bas…

  Authors: Marie-Bernard Debril, Laurent Gelman, Elisabeth Fayard, Jean-Sébastien Annicotte, Stéphane Rocchi, Johan Auwerx

  Source: The Journal of biological chemistry. 2004 Apr 16

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• Fatty aldehyde dehydrogenase: potential role in oxidative stress protection and regulation of its gene expression by insulin.

  Phosphatidylinositol 3-kinase signaling regulates the expression of several genes involved in lipid and glucose homeostasis; deregulation of these gen…

  Authors: Damien Demozay, Stéphane Rocchi, Jean-Christophe Mas, Sophie Grillo, Luciano Pirola, Carine Chavey, Emmanuel Van Obberghen

  Source: The Journal of biological chemistry. 2004 Feb 20

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• Focal adhesion kinase pp125FAK interacts with the large conductance calcium-activated hSlo potassium channel in human osteoblasts: potential role in mechanotransduction.

  Molecular events of mechanotransduction in osteoblasts are poorly defined. We show that the mechanosensitive BK channels open and recruit the focal ad…

  Authors: Roger Rezzonico, Corinne Cayatte, Isabelle Bourget-Ponzio, Georges Romey, Nathalie Belhacene, Agnès Loubat, Stéphane Rocchi, Emmanuel Van Obberghen, Jean-Antoine Girault, Bernard Rossi,…

  Source: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2003 Oct

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