1 to 10 of 15 literature results

• Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.

  We report the results of a meta-analysis of genome-wide association scans for multiple sclerosis (MS) susceptibility that includes 2,624 subjects with…

  Authors: Philip L De Jager, Xiaoming Jia, Joanne Wang, Paul I W de Bakker, Linda Ottoboni, Neelum T Aggarwal, Laura Piccio, Soumya Raychaudhuri, Dong Tran, Cristin Aubin,…

  Source: Nature genetics. 2009 Jul

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• Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk.

  To discover new rheumatoid arthritis (RA) risk loci, we systematically examined 370 SNPs from 179 independent loci with P < 0.001 in a published meta-…

  Authors: Soumya Raychaudhuri, Brian P Thomson, Elaine F Remmers, Stephen Eyre, Anne Hinks, Candace Guiducci, Joseph J Catanese, Gang Xie, Eli A Stahl, Robert Chen,…

  Source: Nature genetics. 2009 Nov 8

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• Common variants at CD40 and other loci confer risk of rheumatoid arthritis.

  To identify rheumatoid arthritis risk loci in European populations, we conducted a meta-analysis of two published genome-wide association (GWA) studie…

  Authors: Soumya Raychaudhuri, Elaine F Remmers, Annette T Lee, Rachel Hackett, Candace Guiducci, Noël P Burtt, Lauren Gianniny, Benjamin D Korman, Leonid Padyukov, Fina A S Kurreeman,…

  Source: Nature genetics. 2008 Oct

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• Practical aspects of imputation-driven meta-analysis of genome-wide association studies.

  Motivated by the overwhelming success of genome-wide association studies, droves of researchers are working vigorously to exchange and to combine gene…

  Authors: Paul I W de Bakker, Manuel A R Ferreira, Xiaoming Jia, Benjamin M Neale, Soumya Raychaudhuri, Benjamin F Voight

  Source: Human molecular genetics. 2008 Oct 15

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• The PRL -1149 G/T polymorphism and rheumatoid arthritis susceptibility.

  OBJECTIVE: Previous studies have demonstrated that the PRL -1149 T (minor) allele decreases prolactin expression and may be associated with autoimmune…

  Authors: Yvonne C Lee, Soumya Raychaudhuri, Jing Cui, Immaculata De Vivo, Bo Ding, Lars Alfredsson, Leonid Padyukov, Karen H Costenbader, Mark Seielstad, Robert R Graham,…

  Source: Arthritis and rheumatism. 2009 May

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• Association of a single-nucleotide polymorphism in CD40 with the rate of joint destruction in rheumatoid arthritis.

  OBJECTIVE: The severity of joint destruction in rheumatoid arthritis (RA) is highly variable from patient to patient and is influenced by genetic fact…

  Authors: Michael P M van der Linden, Anouk L Feitsma, Saskia le Cessie, Marlena Kern, Lina M Olsson, Soumya Raychaudhuri, Ann B Begovich, Monica Chang, Joseph J Catanese, Fina A S Kurreeman,…

  Source: Arthritis and rheumatism. 2009 Aug

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• Using text analysis to identify functionally coherent gene groups.

  The analysis of large-scale genomic information (such as sequence data or expression patterns) frequently involves grouping genes on the basis of comm…

  Authors: Soumya Raychaudhuri, Hinrich Schütze, Russ B Altman

  Source: Genome research. 2002 Oct

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• Associating genes with gene ontology codes using a maximum entropy analysis of biomedical literature.

  Functional characterizations of thousands of gene products from many species are described in the published literature. These discussions are extremel…

  Authors: Soumya Raychaudhuri, Jeffrey T Chang, Patrick D Sutphin, Russ B Altman

  Source: Genome research. 2002 Jan

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• The computational analysis of scientific literature to define and recognize gene expression clusters.

  A limitation of many gene expression analytic approaches is that they do not incorporate comprehensive background knowledge about the genes into the a…

  Authors: Soumya Raychaudhuri, Jeffrey T Chang, Farhad Imam, Russ B Altman

  Source: Nucleic acids research. 2003 Aug 1

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• Investigating hypoxic tumor physiology through gene expression patterns.

  Clinical evidence shows that tumor hypoxia is an independent prognostic indicator of poor patient outcome. Hypoxic tumors have altered physiologic pro…

  Authors: Nicholas C Denko, Lucrezia A Fontana, Karen M Hudson, Patrick D Sutphin, Soumya Raychaudhuri, Russ Altman, Amato J Giaccia

  Source: Oncogene. 2003 Sep 1

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