1 to 10 of 39 literature results

• Activation of phosphatidylcholine cycle enzymes in human epithelial ovarian cancer cells.

  Altered phosphatidylcholine (PC) metabolism in epithelial ovarian cancer (EOC) could provide choline-based imaging approaches as powerful tools to imp…

  Authors: Egidio Iorio, Alessandro Ricci, Marina Bagnoli, Maria Elena Pisanu, Giancarlo Castellano, Massimo Di Vito, Elisa Venturini, Kristine Glunde, Zaver M Bhujwalla, Delia Mezzanzanica,…

  Source: Cancer research. 2010 Mar 1

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• c-FLIPL expression defines two ovarian cancer patient subsets and is a prognostic factor of adverse outcome.

  The impairment of apoptotic pathways represents an efficient mechanism to promote chemoresistance in cancer cells. We previously showed that in epithe…

  Authors: Marina Bagnoli, Federico Ambrogi, Silvana Pilotti, Paola Alberti, Antonino Ditto, Mattia Barbareschi, Enzo Galligioni, Elia Biganzoli, Silvana Canevari, Delia Mezzanzanica

  Source: Endocrine-related cancer. 2009 Jun

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• New potential ligand-receptor signaling loops in ovarian cancer identified in multiple gene expression studies.

  Based on the hypothesis that gene products involved in the same biological process would be coupled at transcriptional level, a previous study analyze…

  Authors: Giancarlo Castellano, James F Reid, Paola Alberti, Maria Luisa Carcangiu, Antonella Tomassetti, Silvana Canevari

  Source: Cancer research. 2006 Nov 15

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• Phosphatidylcholine-specific phospholipase C activation in epithelial ovarian cancer cells.

  Elucidation of the mechanisms responsible for aberrant phosphatidylcholine (PC) metabolism in cancer cells may allow identification of novel biomarker…

  Authors: Francesca Spadaro, Carlo Ramoni, Delia Mezzanzanica, Silvia Miotti, Paola Alberti, Serena Cecchetti, Egidio Iorio, Vincenza Dolo, Silvana Canevari, Franca Podo

  Source: Cancer research. 2008 Aug 15

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• The side population of ovarian cancer cells is a primary target of IFN-alpha antitumor effects.

  The side population (SP), recently identified in several normal tissues and in a variety of tumors based on its ability to extrude some fluorescent dy…

  Authors: Lidia Moserle, Stefano Indraccolo, Margherita Ghisi, Chiara Frasson, Elena Fortunato, Silvana Canevari, Silvia Miotti, Valeria Tosello, Rita Zamarchi, Alberto Corradin,…

  Source: Cancer research. 2008 Jul 15

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• DNA damage-induced cell cycle regulation and function of novel Chk2 phosphoresidues.

  Chk2 kinase is activated by DNA damage to regulate cell cycle arrest, DNA repair, and apoptosis. Phosphorylation of Chk2 in vivo by ataxia telangiecta…

  Authors: Giacomo Buscemi, Luigi Carlessi, Laura Zannini, Sofia Lisanti, Enrico Fontanella, Silvana Canevari, Domenico Delia

  Source: Molecular and cellular biology. 2006 Nov

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• Complement activated by chimeric anti-folate receptor antibodies is an efficient effector system to control ovarian carcinoma.

  Two chimeric monoclonal antibodies (mAb), cMOV18 and cMOV19, recognizing distinct epitopes of folate receptor highly expressed on epithelial ovarian c…

  Authors: Paolo Macor, Delia Mezzanzanica, Chiara Cossetti, Paola Alberti, Mariangela Figini, Silvana Canevari, Francesco Tedesco

  Source: Cancer research. 2006 Apr 1

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• Binding of nuclear caveolin-1 to promoter elements of growth-associated genes in ovarian carcinoma cells.

  Caveolin-1 (cav-1), a member of a protein family associated mainly with cell membrane microdomains in many cell types, acts as a tumor suppressor in o…

  Authors: Elena Sanna, Silvia Miotti, Mimma Mazzi, Giuseppina De Santis, Silvana Canevari, Antonella Tomassetti

  Source: Experimental cell research. 2007 Apr 15

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• Alterations of choline phospholipid metabolism in ovarian tumor progression.

  Recent characterization of abnormal phosphatidylcholine metabolism in tumor cells by nuclear magnetic resonance (NMR) has identified novel fingerprint…

  Authors: Egidio Iorio, Delia Mezzanzanica, Paola Alberti, Francesca Spadaro, Carlo Ramoni, Sandra D'Ascenzo, Danilo Millimaggi, Antonio Pavan, Vincenza Dolo, Silvana Canevari,…

  Source: Cancer research. 2005 Oct 15

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• The variant hepatocyte nuclear factor 1 activates the P1 promoter of the human alpha-folate receptor gene in ovarian carcinoma.

  The alpha folate receptor (alpha FR) is a membrane glycoprotein that binds folates, and mediates their uptake and that of antifolate drugs. alpha FR i…

  Authors: Antonella Tomassetti, Fabio Mangiarotti, Mimma Mazzi, Sabrina Sforzini, Silvia Miotti, Enrico Galmozzi, Patrick C Elwood, Silvana Canevari

  Source: Cancer research. 2003 Feb 1

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