1 to 10 of 24 literature results

• Toll-like receptors on hematopoietic progenitor cells stimulate innate immune system replenishment.

  Toll-like receptors (TLRs) are best known for their ability to recognize microbial or viral components and initiate innate immune responses. We showed…

  Authors: Yoshinori Nagai, Karla P Garrett, Shoichiro Ohta, Uleng Bahrun, Taku Kouro, Shizuo Akira, Kiyoshi Takatsu, Paul W Kincade

  Source: Immunity. 2006 Jun

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• Evidence for lack of enhanced hedgehog target gene expression in common extracutaneous tumors.

  Abnormal hedgehog signaling, most commonly caused by loss of PTCH1 inhibitor activity,drives tumorigenesis of basal cell carcinomas (BCCs). To assess …

  Authors: Zhilan Hu, Jeannette M Bonifas, Geraldine Aragon, Levy Kopelovich, Yu Liang, Shoichiro Ohta, Mark A Israel, David R Bickers, Michelle Aszterbaum, Ervin H Epstein

  Source: Cancer research. 2003 Mar 1

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• Metastasis-associated gene expression profile of liver and subcutaneous lesions derived from mouse pheochromocytoma cells.

  The development of metastatic cancer is associated with overexpression or downregulation of specific genes and cell regulatory pathways. Some of these…

  Authors: Shoichiro Ohta, Edwin W Lai, John C Morris, Alan L Y Pang, Morihiro Watanabe, Hiroshi Yazawa, Richard Zhang, Jeffery E Green, Wai-Yee Chan, Paul Sirajuddin,…

  Source: Molecular carcinogenesis. 2008 Apr

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• Animal models of pheochromocytoma including NIH initial experience.

  Mouse models have been used to study the mechanisms underlying the carcinogenesis of a wide variety of human cancer. A considerable number of mouse an…

  Authors: Shoichiro Ohta, Edwin W Lai, Shun'Ichiro Taniguchi, Arthur S Tischler, Salvatore Alesci, Karel Pacak

  Source: Annals of the New York Academy of Sciences. 2006 Aug

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• Identification of a novel isoform of MD-2 that downregulates lipopolysaccharide signaling.

  MD-2 is an association molecule of Toll-like receptor 4 and is indispensable for the recognition of lipopolysaccharide. Here we report the identificat…

  Authors: Shoichiro Ohta, Uleng Bahrun, Mariko Tanaka, Masao Kimoto

  Source: Biochemical and biophysical research communications. 2004 Oct 22

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• Squamous cell carcinoma antigen 1 is an inhibitor of parasite-derived cysteine proteases.

  The physiological significance of the squamous cell carcinoma antigens 1 (SCCA1) and SCCA2, members of the ovalbumin serpin family, remains unresolved…

  Authors: Sachiko Kanaji, Yoko Tanaka, Yasuhisa Sakata, Kohei Takeshita, Kazuhiko Arima, Shoichiro Ohta, Elizabeth J Hansell, Conor Caffrey, Jeremy C Mottram, Jonathan Lowther,…

  Source: FEBS letters. 2007 Sep 4

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• Tissue factor expression and prognosis in patients with metastatic prostate cancer.

  OBJECTIVES: To assess immunohistochemically the pattern of tissue factor (TF) expression in patients with metastatic prostate cancer, because TF is ab…

  Authors: Takuya Akashi, Yuzo Furuya, Shoichiro Ohta, Hideki Fuse

  Source: Urology. 2003 Dec

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• Gender-related differences in the clinical presentation of malignant and benign pheochromocytoma.

  Signs and symptoms associated with pheochromocytomas are predominantly caused by catecholamine excess, but tend to be highly variable and non-specific…

  Authors: Edwin W Lai, Shiromi M Perera, Bas Havekes, Henri J L M Timmers, Frederieke M Brouwers, Beverly McElroy, Karen T Adams, Shoichiro Ohta, Robert A Wesley, Graeme Eisenhofer,…

  Source: Endocrine. 2008 Aug-Dec

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• Anatomical and functional imaging of tumors in animal models: focus on pheochromocytoma.

  This review focuses on anatomical (computed tomography, magnetic resonance imaging) and functional (positron emission tomography) imaging methods for …

  Authors: Lucia Martiniova, Shoichiro Ohta, Peter Guion, Daniel Schimel, Edwin W Lai, Brenda Klaunberg, Elaine Jagoda, Karel Pacak

  Source: Annals of the New York Academy of Sciences. 2006 Aug

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• Identification of four novel mutations in F5 associated with congenital factor V deficiency.

  Coagulation factor V (FV) deficiency is a rare bleeding disorder characterized by low coagulant and antigen levels of FV with bleeding symptoms rangin…

  Authors: Sachiko Kanaji, Taisuke Kanaji, Miho Honda, Sachie Nakazato, Kazuo Wakayama, Yoshitomi Tabata, Shoichiro Shibata, Hisashi Gondo, Ikuko Nakamura, Koichi Node,…

  Source: International journal of hematology. 2009 Jan

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