1 to 10 of 30 literature results

• Regulation of endoplasmic reticulum stress response by a BBF2H7-mediated Sec23a pathway is essential for chondrogenesis.

  Many tissues have a specific signal transduction system for endoplasmic reticulum (ER) dysfunction; however, the mechanisms underlying the ER stress r…

  Authors: Atsushi Saito, Shin-ichiro Hino, Tomohiko Murakami, Soshi Kanemoto, Shinichi Kondo, Masahiro Saitoh, Riko Nishimura, Toshiyuki Yoneda, Tatsuya Furuichi, Shiro Ikegawa,…

  Source: Nature cell biology. 2009 Oct

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• Signalling mediated by the endoplasmic reticulum stress transducer OASIS is involved in bone formation.

  Eukaryotic cells have signalling pathways from the endoplasmic reticulum (ER) to cytosol and nuclei, to avoid excess accumulation of unfolded proteins…

  Authors: Tomohiko Murakami, Atsushi Saito, Shin-ichiro Hino, Shinichi Kondo, Soshi Kanemoto, Kazuyasu Chihara, Hiroshi Sekiya, Kenji Tsumagari, Kimiko Ochiai, Kazuya Yoshinaga,…

  Source: Nature cell biology. 2009 Oct

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• OASIS, a CREB/ATF-family member, modulates UPR signalling in astrocytes.

  Endoplasmic reticulum (ER) stress transducers IRE1, PERK and ATF6 are well known to transduce signals from the ER to the cytoplasm and nucleus when un…

  Authors: Shinichi Kondo, Tomohiko Murakami, Kouko Tatsumi, Maiko Ogata, Soshi Kanemoto, Kumi Otori, Ken Iseki, Akio Wanaka, Kazunori Imaizumi

  Source: Nature cell biology. 2005 Feb

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• Molecular mechanisms responsible for aberrant splicing of SERCA1 in myotonic dystrophy type 1.

  Myotonic dystrophy type 1 (DM1) is an autosomal dominant neuromuscular disorder associated with an expansion of CTG trinucleotide repeats in the 3'-un…

  Authors: Shin-Ichiro Hino, Shinichi Kondo, Hiroshi Sekiya, Atsushi Saito, Soshi Kanemoto, Tomohiko Murakami, Kazuyasu Chihara, Yuri Aoki, Masayuki Nakamori, Masanori P Takahashi,…

  Source: Human molecular genetics. 2007 Dec 1

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• BBF2H7, a novel transmembrane bZIP transcription factor, is a new type of endoplasmic reticulum stress transducer.

  Endoplasmic reticulum (ER) stress transducers IRE1 (inositol requiring 1), PERK (PKR-like endoplasmic reticulum kinase), and ATF6 (activating transcri…

  Authors: Shinichi Kondo, Atsushi Saito, Shin-Ichiro Hino, Tomohiko Murakami, Maiko Ogata, Soshi Kanemoto, Satoshi Nara, Akinori Yamashita, Kazuya Yoshinaga, Hideaki Hara,…

  Source: Molecular and cellular biology. 2007 Mar

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• Autophagy is activated for cell survival after endoplasmic reticulum stress.

  Eukaryotic cells deal with accumulation of unfolded proteins in the endoplasmic reticulum (ER) by the unfolded protein response, involving the inducti…

  Authors: Maiko Ogata, Shin-ichiro Hino, Atsushi Saito, Keisuke Morikawa, Shinichi Kondo, Soshi Kanemoto, Tomohiko Murakami, Manabu Taniguchi, Ichiro Tanii, Kazuya Yoshinaga,…

  Source: Molecular and cellular biology. 2006 Dec

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• A novel ER stress transducer, OASIS, expressed in astrocytes.

  Secretory and transmembrane proteins are correctly folded or processed in the endoplasmic reticulum (ER). Various stresses disturb ER function and pro…

  Authors: Atsushi Saito, Shin-Ichiro Hino, Tomohiko Murakami, Shinichi Kondo, Kazunori Imaizumi

  Source: Antioxidants & redox signaling. 2007 May

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• Cleavage of the membrane-bound transcription factor OASIS in response to endoplasmic reticulum stress.

  When unfolded or misfolded proteins accumulate in the endoplasmic reticulum (ER), unfolded protein response (UPR) signals are transmitted from the ER …

  Authors: Tomohiko Murakami, Shinichi Kondo, Maiko Ogata, Soshi Kanemoto, Atsushi Saito, Akio Wanaka, Kazunori Imaizumi

  Source: Journal of neurochemistry. 2006 Feb

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• Regulation of ER molecular chaperone prevents bone loss in a murine model for osteoporosis.

  Endoplasmic reticulum (ER) stress response is important for protein maturation in the ER. Some murine models for bone diseases have provided significa…

  Authors: Shin-ichiro Hino, Shinichi Kondo, Kazuya Yoshinaga, Atsushi Saito, Tomohiko Murakami, Soshi Kanemoto, Hiroshi Sekiya, Kazuyasu Chihara, Yuji Aikawa, Hideaki Hara,…

  Source: Journal of bone and mineral metabolism. 2010 Mar

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• XBP1 activates the transcription of its target genes via an ACGT core sequence under ER stress.

  In mammals, the transmembrane protein kinase/endoribonuclease IRE1 is activated by endoplasmic reticulum stress and subsequently processes XBP1 mRNA t…

  Authors: Soshi Kanemoto, Shinichi Kondo, Maiko Ogata, Tomohiko Murakami, Fumihiko Urano, Kazunori Imaizumi

  Source: Biochemical and biophysical research communications. 2005 Jun 17

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