1 to 2 of 2 literature results

• The contribution of transcription factor IRF1 to the interferon-gamma-interleukin 12 signaling axis and TH1 versus TH-17 differentiation of CD4+ T cells.

  Interleukin-12 (IL-12) and interferon-gamma (IFN-gamma) drive T helper type 1 (T(H)1) differentiation, but the mechanisms underlying the regulation of…

  Authors: Shin-ichi Kano, Kojiro Sato, Yasuyuki Morishita, Sabine Vollstedt, Sunhwa Kim, Keith Bishop, Kenya Honda, Masato Kubo, Tadatsugu Taniguchi

  Source: Nature immunology. 2008 Jan

  View Full Text

• Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors.

  The activation of Toll-like receptors (TLRs) is central to innate and adaptive immunity. All TLRs use the adaptor MyD88 for signalling, but the mechan…

  Authors: Akinori Takaoka, Hideyuki Yanai, Seiji Kondo, Gordon Duncan, Hideo Negishi, Tatsuaki Mizutani, Shin-Ichi Kano, Kenya Honda, Yusuke Ohba, Tak W Mak,…

  Source: Nature. 2005 Mar 10

  View Full Text