1 to 4 of 4 literature results

• A direct functional link between the multi-PDZ domain protein GRIP1 and the Fraser syndrome protein Fras1.

  Cell adhesion to extracellular matrix (ECM) proteins is crucial for the structural integrity of tissues and epithelial-mesenchymal interactions mediat…

  Authors: Kogo Takamiya, Vassiliki Kostourou, Susanne Adams, Shalini Jadeja, Georges Chalepakis, Peter J Scambler, Richard L Huganir, Ralf H Adams

  Source: Nature genetics. 2004 Feb

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• Identification of a new gene mutated in Fraser syndrome and mouse myelencephalic blebs.

  Fraser syndrome is a recessive, multisystem disorder presenting with cryptophthalmos, syndactyly and renal defects and associated with loss-of-functio…

  Authors: Shalini Jadeja, Ian Smyth, Jolanta E Pitera, Martin S Taylor, Mieke van Haelst, Elizabeth Bentley, Lesley McGregor, Jason Hopkins, Georges Chalepakis, Nicole Philip,…

  Source: Nature genetics. 2005 May

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• Fraser syndrome and mouse blebbed phenotype caused by mutations in FRAS1/Fras1 encoding a putative extracellular matrix protein.

  Fraser syndrome (OMIM 219000) is a multisystem malformation usually comprising cryptophthalmos, syndactyly and renal defects. Here we report autozygos…

  Authors: Lesley McGregor, Ville Makela, Susan M Darling, Sofia Vrontou, Georges Chalepakis, Catherine Roberts, Nicola Smart, Paul Rutland, Natalie Prescott, Jason Hopkins,…

  Source: Nature genetics. 2003 Jun

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• Efficient, inducible Cre-recombinase activation in vascular endothelium.

  In recent years, gene-targeting studies in mice have elucidated many molecular mechanisms in vascular biology. However, it has been difficult to apply…

  Authors: Suzanne Claxton, Vassiliki Kostourou, Shalini Jadeja, Pierre Chambon, Kairbaan Hodivala-Dilke, Marcus Fruttiger

  Source: Genesis (New York, N.Y. : 2000). 2008 Feb

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