1 to 6 of 6 literature results

• Copper compounds in anticancer strategies.

  The chemical properties of copper allow it to take part in many biological functions such as electron transfer, catalysis, and structural shaping. The…

  Authors: Saverio Tardito, Luciano Marchiò

  Source: Current medicinal chemistry. 2009

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• TOE1 interacts with p53 to modulate its transactivation potential.

  The TOE1 gene was discovered as a target of the Egr1 transcription factor that participates in cell growth regulation through the upregulation of p21 …

  Authors: Sabina Sperandio, Saverio Tardito, Aleksandra Surzycki, Martin Latterich, Ian de Belle

  Source: FEBS letters. 2009 Jul 7

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• Thioamido coordination in a thioxo-1,2,4-triazole copper(II) complex enhances nonapoptotic programmed cell death associated with copper accumulation and oxidative stress in human cancer cells.

  The thioamido function of [CuCl2(1H)]Cl (2) (1=4-amino-1,4-dihydro-3-(2-pyridyl)-5-thioxo-1,2,4-triazole), a cytotoxic copper complex, was converted i…

  Authors: Saverio Tardito, Ovidio Bussolati, Monica Maffini, Matteo Tegoni, Marco Giannetto, Valeria Dall'asta, Renata Franchi-Gazzola, Maurizio Lanfranchi, Maria Angela Pellinghelli, Claudio Mucchino,…

  Source: Journal of medicinal chemistry. 2007 Apr 19

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• Synthesis, solution equilibria and antiproliferative activity of copper(II) aminomethyltriazole and aminomethylthioxotriazoline complexes.

  The aim of the present study was the synthesis, the determination of formation constants, and the evaluation of the antiproliferative activity of two …

  Authors: Francesca Gaccioli, Renata Franchi-Gazzola, Maurizio Lanfranchi, Luciano Marchiò, Giuseppe Metta, Maria Angela Pellinghelli, Saverio Tardito, Matteo Tegoni

  Source: Journal of inorganic biochemistry. 2005 Aug

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• Synthesis, structural characterisation and solution chemistry of ruthenium(III) triazole-thiadiazine complexes.

  Two ruthenium(III) complexes structurally similar to the anticancer compound NAMI were prepared: Na[RuCl4(DMSO)(L1)] ( 1) and Na[RuCl4(DMSO)(L2)] ( 2)…

  Authors: Massimiliano Delferro, Luciano Marchiò, Matteo Tegoni, Saverio Tardito, Renata Franchi-Gazzola, Maurizio Lanfranchi

  Source: Dalton transactions (Cambridge, England : 2003). 2009 May 21

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• The thioxotriazole copper(II) complex A0 induces endoplasmic reticulum stress and paraptotic death in human cancer cells.

  The copper(II) complex A0 induces a type of non-apoptotic cell death also known as paraptosis. Paraptosis involves extensive endoplasmic reticulum vac…

  Authors: Saverio Tardito, Claudio Isella, Enzo Medico, Luciano Marchiò, Elena Bevilacqua, Maria Hatzoglou, Ovidio Bussolati, Renata Franchi-Gazzola

  Source: The Journal of biological chemistry. 2009 Sep 4

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