1 to 3 of 3 literature results

• Drosophila Ric-8 is essential for plasma-membrane localization of heterotrimeric G proteins.

  Heterotrimeric G proteins act during signal transduction in response to extracellular ligands. They are also required for spindle orientation and cell…

  Authors: Bernhard Hampoelz, Oliver Hoeller, Sarah K Bowman, Dara Dunican, Juergen A Knoblich

  Source: Nature cell biology. 2005 Nov

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• The tumor suppressors Brat and Numb regulate transit-amplifying neuroblast lineages in Drosophila.

  In both vertebrates and insects, neurons typically arise from neural stem cells or terminally dividing intermediate progenitors. Here, we describe ano…

  Authors: Sarah K Bowman, Vivien Rolland, Joerg Betschinger, Kaolin A Kinsey, Gregory Emery, Juergen A Knoblich

  Source: Developmental cell. 2008 Apr

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• The Drosophila NuMA Homolog Mud regulates spindle orientation in asymmetric cell division.

  During asymmetric cell division, the mitotic spindle must be properly oriented to ensure the asymmetric segregation of cell fate determinants into onl…

  Authors: Sarah K Bowman, Ralph A Neumüller, Maria Novatchkova, Quansheng Du, Juergen A Knoblich

  Source: Developmental cell. 2006 Jun

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