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• Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells.

  Imatinib mesylate (IM), a potent inhibitor of the BCR/ABL tyrosine kinase, has become standard first-line therapy for patients with chronic myeloid le…

  Authors: Cristian Bellodi, Maria Rosa Lidonnici, Ashley Hamilton, G Vignir Helgason, Angela Rachele Soliera, Mattia Ronchetti, Sara Galavotti, Kenneth W Young, Tommaso Selmi, Rinat Yacobi,…

  Source: The Journal of clinical investigation. 2009 May

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