1 to 9 of 9 literature results

• A luminal epithelial stem cell that is a cell of origin for prostate cancer.

  In epithelial tissues, the lineage relationship between normal progenitor cells and cell type(s) of origin for cancer has been poorly understood. Here…

  Authors: Xi Wang, Marianna Kruithof-de Julio, Kyriakos D Economides, David Walker, Hailong Yu, M Vivienne Halili, Ya-Ping Hu, Sandy M Price, Cory Abate-Shen, Michael M Shen

  Source: Nature. 2009 Sep 24

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• Monomethylation of histone H4-lysine 20 is involved in chromosome structure and stability and is essential for mouse development.

  PR-Set7/Set8/KMT5A is the sole enzyme known to catalyze monomethylation of histone H4 lysine 20 (H4K20) and is present only in multicellular organisms…

  Authors: Hisanobu Oda, Ikuhiro Okamoto, Niall Murphy, Jianhua Chu, Sandy M Price, Michael M Shen, Maria Elena Torres-Padilla, Edith Heard, Danny Reinberg

  Source: Molecular and cellular biology. 2009 Apr

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• Foxn4 controls the genesis of amacrine and horizontal cells by retinal progenitors.

  During vertebrate retinogenesis, seven classes of cells are specified from multipotent progenitors. To date, the mechanisms underlying multipotent cel…

  Authors: Shengguo Li, Zeqian Mo, Xuejie Yang, Sandy M Price, Michael M Shen, Mengqing Xiang

  Source: Neuron. 2004 Sep 16

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• Mouse Fem1b interacts with the Nkx3.1 homeoprotein and is required for proper male secondary sexual development.

  Previous studies of epithelial cell growth and differentiation in the prostate gland have identified the homeodomain protein Nkx3.1 as a central regul…

  Authors: Xi Wang, Nishita Desai, Ya-Ping Hu, Sandy M Price, Cory Abate-Shen, Michael M Shen

  Source: Developmental dynamics : an official publication of the American Association of Anatomists. 2008 Oct

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• Barhl1 regulates migration and survival of cerebellar granule cells by controlling expression of the neurotrophin-3 gene.

  The neurons generated at the germinal rhombic lip undergo long distance migration along divergent pathways to settle in widely dispersed locations wit…

  Authors: Shengguo Li, Feng Qiu, Anlong Xu, Sandy M Price, Mengqing Xiang

  Source: The Journal of neuroscience : the official journal of the Society for Neuroscience. 2004 Mar 24

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• Non-cell-autonomous role for Cripto in axial midline formation during vertebrate embryogenesis.

  Several membrane-associated proteins are known to modulate the activity and range of potent morphogenetic signals during development. In particular, m…

  Authors: Jianhua Chu, Jixiang Ding, Katherine Jeays-Ward, Sandy M Price, Marysia Placzek, Michael M Shen

  Source: Development (Cambridge, England). 2005 Dec

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• Genetic evidence for nonredundant functional cooperativity between NPC1 and NPC2 in lipid transport.

  Niemann-Pick C (NPC) disease is a fatal neurodegenerative disorder characterized by a lysosomal accumulation of cholesterol and other lipids within th…

  Authors: David E Sleat, Jennifer A Wiseman, Mukarram El-Banna, Sandy M Price, Lucie Verot, Michael M Shen, G Stephen Tint, Marie T Vanier, Steven U Walkley, Peter Lobel

  Source: Proceedings of the National Academy of Sciences of the United States of America. 2004 Apr 20

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• Hearing loss caused by progressive degeneration of cochlear hair cells in mice deficient for the Barhl1 homeobox gene.

  The cochlea of the mammalian inner ear contains three rows of outer hair cells and a single row of inner hair cells. These hair cell receptors reside …

  Authors: Shengguo Li, Sandy M Price, Hugh Cahill, David K Ryugo, Michael M Shen, Mengqing Xiang

  Source: Development (Cambridge, England). 2002 Jul

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• Inhibition of excess nodal signaling during mouse gastrulation by the transcriptional corepressor DRAP1.

  The formation and patterning of mesoderm during mammalian gastrulation require the activity of Nodal, a secreted mesoderm-inducing factor of the trans…

  Authors: Rabah Iratni, Yu-Ting Yan, Canhe Chen, Jixiang Ding, Yi Zhang, Sandy M Price, Danny Reinberg, Michael M Shen

  Source: Science (New York, N.Y.). 2002 Dec 6

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