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The additional benefit of the ML Flow test to classify leprosy patients.
The use of the skin lesion counting classification leads to both under and over diagnosis of leprosy in many instances. Thus, there is a need to compl…
Authors: Samira Bührer-Sékula, Ximena Illarramendi, Rose B Teles, Maria Lucia F Penna, José Augusto C Nery, Anna Maria Sales, Linda Oskam, Elizabeth P Sampaio, Euzenir N Sarno
Source: Acta tropica. 2009 Aug
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Postgenomic approach to identify novel Mycobacterium leprae antigens with potential to improve immunodiagnosis of infection.
Early detection of Mycobacterium leprae infection is considered an important component of strategies aiming at reducing transmission of infection, but…
Authors: Annemieke Geluk, Michèl R Klein, Kees L M C Franken, Krista E van Meijgaarden, Brigitte Wieles, Kelly Cristina Pereira, Samira Bührer-Sékula, Paul R Klatser, Patrick J Brennan, John S Spencer,…
Source: Infection and immunity. 2005 Sep
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A comparison of ML Flow serology and slit skin smears to assess the bacterial load in newly diagnosed leprosy patients in Brazil.
INTRODUCTION: The ML Flow test is an immunochromatographic assay that detects IgM antibodies against M. leprae-specific anti-phenolic glycolipid I (PG…
Authors: Sandra Lyon, Ana Claudia Lyon, Rozana Castorina Da Silva, Maria Aparecida De Faria Grossi, Silvia Helena Lyon, Samira Bührer-Sékula, Manoel O C Rocha
Source: Leprosy review. 2008 Jun
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The ML flow test as a point of care test for leprosy control programmes: potential effects on classification of leprosy patients.
OBJECTIVE: To evaluate the use of the ML Flow test as an additional, serological, tool for the classification of new leprosy patients. DESIGN: In Braz…
Authors: Samira Bührer-Sékula, Jan Visschedijk, Maria Aparecida F Grossi, Krishna P Dhakal, Abdullahi U Namadi, Paul R Klatser, Linda Oskam
Source: Leprosy review. 2007 Mar
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Leprosy serology (ML Flow test) in borderline leprosy patients classified as paucibacillary by counting cutaneous lesions: an useful tool.
Leprosy remains an endemic disease in Brazil, with almost 40,000 new cases diagnosed each year. As it is difficult to perform laboratory procedures in…
Authors: Jaison Antônio Barreto, Maria Esther Salles Nogueira, Suzana Madeira Diorio, Samira Bührer-Sékula
Source: Revista da Sociedade Brasileira de Medicina Tropical. 2008
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Leprosy serology using PGL-I: a systematic review.
Serology using a species-specific antigen for Mycobacterium leprae, PGL-I, could be a marker for the bacterial load of patients with leprosy. Various …
Authors: Rodrigo Scaliante de Moura, Karla Lucena Calado, Maria Leide W Oliveira, Samira Bührer-Sékula
Source: Revista da Sociedade Brasileira de Medicina Tropical. 2008
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The use of serology as an additional tool to support diagnosis of difficult multibacillary leprosy cases: lessons from clinical care.
Seven multibacillary leprosy and two suspected cases assisted in different situations during clinical care activities at the university in Rio de Jane…
Authors: Maria Leide W Oliveira, Flávia Amorim Meira Cavaliére, Juan Manoel Pineiro Maceira, Samira Bührer-Sékula
Source: Revista da Sociedade Brasileira de Medicina Tropical. 2008
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Seroprevalence of ML Flow test in leprosy contacts from State of Minas Gerais, Brazil.
Leprosy is a public health problem in Brazil. Epidemiological control actions are based on the diagnosis and treatment of leprosy patients and househo…
Authors: Ana Regina Coelho de Andrade, Maria Aparecida de Faria Grossi, Samira Bührer-Sékula, Carlos Maurício Figueiredo Antunes
Source: Revista da Sociedade Brasileira de Medicina Tropical. 2008
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Risk factors for ML Flow seropositivity in leprosy patients.
The early diagnosis of leprosy, its correct classification and the risk factors related to seropositivity have become important for patient treatment …
Authors: Maria Aparecida de Faria Grossi, Maria Ana Araújo Leboeuf, Ana Regina Coelho de Andrade, Samira Bührer-Sékula, Carlos Maurício de Figueiredo Antunes
Source: Revista da Sociedade Brasileira de Medicina Tropical. 2008
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Association between leprosy reactions after treatment and bacterial load evaluated using anti PGL-I serology and bacilloscopy.
Leprosy (Hansen's disease, HD) reactions are immune-inflammatory phenomena that occur during the evolution of the disease. Given the current criteria …
Authors: Maria de Fátima de Medeiros Brito, Ricardo Arraes Alencar Ximenes, Maria Eugênia Noviski Gallo, Samira Bührer-Sékula
Source: Revista da Sociedade Brasileira de Medicina Tropical. 2008
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