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1 to 6 of 6 literature results
The apical protease of the human intrinsic apoptotic pathway, caspase-9, is activated in a polymeric activation platform known as the apoptosome. The …
Authors: Cristina Pop, John Timmer, Sabina Sperandio, Guy S Salvesen
Source: Molecular cell. 2006 Apr 21
View Full TextThe TOE1 gene was discovered as a target of the Egr1 transcription factor that participates in cell growth regulation through the upregulation of p21 …
Authors: Sabina Sperandio, Saverio Tardito, Aleksandra Surzycki, Martin Latterich, Ian de Belle
Source: FEBS letters. 2009 Jul 7
View Full TextApoptosis is orchestrated by the concerted action of caspases, activated in a minimal two-step proteolytic cascade. Existing data suggests that apical…
Authors: Kelly M Boatright, Martin Renatus, Fiona L Scott, Sabina Sperandio, Hwain Shin, Irene M Pedersen, Jean Ehrland Ricci, Wade A Edris, Daniel P Sutherlin, Douglas R Green,…
Source: Molecular cell. 2003 Feb
View Full TextUsing oligonucleotide expression microarrays we have examined the modulation of gene expression in the DU145 prostate cancer cell line. Our findings c…
Authors: Sabina Sperandio, Jessyka Fortin, Roman Sasik, Lynda Robitaille, Jacques Corbeil, Ian de Belle
Source: Molecular carcinogenesis. 2009 Jan
View Full TextThe type 1 insulin-like growth factor receptor (IGF-IR) is a receptor-tyrosine kinase that plays a critical role in signaling cell survival and prolif…
Authors: Veronica Galvan, Anna Logvinova, Sabina Sperandio, Hidenori Ichijo, Dale E Bredesen
Source: The Journal of biological chemistry. 2003 Apr 11
View Full TextEgr1, an immediate early transcription factor, responds to diverse stimuli and affects gene transcription to accomplish its biological effects. One im…
Authors: Ian De Belle, Jie-Xin Wu, Sabina Sperandio, Dan Mercola, Eileen D Adamson
Source: The Journal of biological chemistry. 2003 Apr 18
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