1 to 10 of 1,263 literature results

• Peierls distortion as a route to high thermoelectric performance in In(4)Se(3-delta) crystals.

  Thermoelectric energy harvesting-the transformation of waste heat into useful electricity-is of great interest for energy sustainability. The main obs…

  Authors: Jong-Soo Rhyee, Kyu Hyoung Lee, Sang Mock Lee, Eunseog Cho, Sang Il Kim, Eunsung Lee, Yong Seung Kwon, Ji Hoon Shim, Gabriel Kotliar

  Source: Nature. 2009 Jun 18

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• Rab35 mediates transport of Cdc42 and Rac1 to the plasma membrane during phagocytosis.

  Phagocytosis of invading microbes requires dynamic rearrangement of the plasma membrane and its associated cytoskeletal actin network. The polarizatio…

  Authors: Jaewon Shim, Sun-Min Lee, Myeong Sup Lee, Joonsun Yoon, Hee-Seok Kweon, Young-Joon Kim

  Source: Molecular and cellular biology. 2010 Jan 11

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• FoxP3 maintains Treg unresponsiveness by selectively inhibiting the promoter DNA-binding activity of AP-1.

  Regulatory T cells (Tregs) have been shown to play a crucial role in maintaining self-tolerance and suppressing autoimmunity. The forkhead transcripti…

  Authors: Sang-Myeong Lee, Beixue Gao, Deyu Fang

  Source: Blood. 2008 Apr 1

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• RLE-1, an E3 ubiquitin ligase, regulates C. elegans aging by catalyzing DAF-16 polyubiquitination.

  The forkhead transcription factor, DAF-16, a downstream target of the insulin/IGF-I signaling pathway in C. elegans, is indispensable both for lifespa…

  Authors: Wensheng Li, Beixue Gao, Sang-Myeong Lee, Karen Bennett, Deyu Fang

  Source: Developmental cell. 2007 Feb

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• p53 stabilization and transactivation by a von Hippel-Lindau protein.

  von Hippel-Lindau (VHL) disease is a rare autosomal dominant cancer syndrome. Although hypoxia-inducible factor-alpha (HIFalpha) is a well-documented …

  Authors: Jae-Seok Roe, Hyungsoo Kim, Soon-Min Lee, Sung-Tae Kim, Eun-Jung Cho, Hong-Duk Youn

  Source: Molecular cell. 2006 May 5

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• Protective role of autophagy in palmitate-induced INS-1 beta-cell death.

  Autophagy, a vacuolar degradative pathway, constitutes a stress adaptation that avoids cell death or elicits the alternative cell-death pathway. This …

  Authors: Sung-E Choi, Sung-Mi Lee, Youn-Jung Lee, Ling-Ji Li, Soo-Jin Lee, Ji-Hyun Lee, Youngsoo Kim, Hee-Sook Jun, Kwan-Woo Lee, Yup Kang

  Source: Endocrinology. 2009 Jan

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• Anti-angiogenic therapy using thalidomide combined with chemotherapy in small cell lung cancer: a randomized, double-blind, placebo-controlled trial.

  BACKGROUND: Cancer cells rely on angiogenesis for growth and dissemination, and small cell lung cancer (SCLC) is a highly angiogenic tumor. We evaluat…

  Authors: Siow Ming Lee, Penella J Woll, Robin Rudd, David Ferry, Mary O'Brien, Gary Middleton, Stephen Spiro, Lindsay James, Kulsam Ali, Mark Jitlal,…

  Source: Journal of the National Cancer Institute. 2009 Aug 5

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• Clickable" polymer-caged nanobins as a modular drug delivery platform.

  Modularly clickable polymer-caged nanobins (PCNs) were prepared from liposome templates using a drop-in cholesterol-modified poly(acrylic acid) reagen…

  Authors: Sang-Min Lee, Haimei Chen, Thomas V O'Halloran, SonBinh T Nguyen

  Source: Journal of the American Chemical Society. 2009 Jul 8

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• A nucleocytoplasmic malate dehydrogenase regulates p53 transcriptional activity in response to metabolic stress.

  Metabolic enzymes have been shown to function as transcriptional regulators. p53, a tumor-suppressive transcription factor, was recently found to regu…

  Authors: S M Lee, J H Kim, E J Cho, H D Youn

  Source: Cell death and differentiation. 2009 May

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• The ubiquitin ligase gp78 promotes sarcoma metastasis by targeting KAI1 for degradation.

  Metastasis is the primary cause of mortality from cancer, but the mechanisms leading to metastasis are poorly understood. In particular, relatively li…

  Authors: Yien Che Tsai, Arnulfo Mendoza, Jennifer M Mariano, Ming Zhou, Zlatka Kostova, Bo Chen, Timothy Veenstra, Stephen M Hewitt, Lee J Helman, Chand Khanna,…

  Source: Nature medicine. 2007 Dec

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