1 to 10 of 50 literature results

• Therapeutic potential of interleukin-15: a myokine involved in muscle wasting and adiposity.

  Since the discovery of IL-15 and its role in T-cell proliferation in 1994, different studies on the effects of the cytokine on metabolic effects have …

  Authors: Josep M Argilés, Francisco J López-Soriano, Sílvia Busquets

  Source: Drug discovery today. 2009 Feb

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• Novel approaches to the treatment of cachexia.

  Cachexia is a complex syndrome. The main components of this pathological state are anorexia and metabolic abnormalities, such as glucose intolerance, …

  Authors: Josep M Argilés, Francisco J López-Soriano, Sílvia Busquets

  Source: Drug discovery today. 2008 Jan

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• Are peroxisome proliferator-activated receptors involved in skeletal muscle wasting during experimental cancer cachexia? Role of beta2-adrenergic agonists.

  Implantation of the Yoshida AH-130 ascites hepatoma to rats resulted in a decrease in muscle weight 7 days after the inoculation of the tumor. These c…

  Authors: Gemma Fuster, Sílvia Busquets, Elisabet Ametller, Mireia Olivan, Vanessa Almendro, Cibely Cristine Fontes de Oliveira, Maite Figueras, Francisco J López-Soriano, Josep M Argilés

  Source: Cancer research. 2007 Jul 1

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• Cross-talk between skeletal muscle and adipose tissue: a link with obesity?

  Since the discovery of leptin, the adipocyte and its products have been the subject of intensive research. Thus, it has been demonstrated that adipose…

  Authors: Josep M Argilés, Joaquín López-Soriano, Vanessa Almendro, Sílvia Busquets, Francisco J López-Soriano

  Source: Medicinal research reviews. 2005 Jan

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• Redox balance and carbonylated proteins in limb and heart muscles of cachectic rats.

  In fast- and slow-twitch limb and heart muscles of cachectic rats, redox balance and muscle structure were explored. The nature of the oxidatively mod…

  Authors: Judith Marin-Corral, Cibely C Fontes, Sergi Pascual-Guardia, Francisco Sanchez, Mireia Olivan, Josep M Argilés, Sílvia Busquets, Francisco J López-Soriano, Esther Barreiro

  Source: Antioxidants & redox signaling. 2010 Mar

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• UCP3 overexpression neutralizes oxidative stress rather than nitrosative stress in mouse myotubes.

  The deleterious effects of oxidants on proteins may be modified by overexpression of uncoupling protein 3 (UCP3) in skeletal muscle cells exposed to h…

  Authors: Esther Barreiro, Cèlia Garcia-Martínez, Sandra Mas, Elisabet Ametller, Joaquim Gea, Josep M Argilés, Sílvia Busquets, Francisco J López-Soriano

  Source: FEBS letters. 2009 Jan 22

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• Anticachectic effects of formoterol: a drug for potential treatment of muscle wasting.

  In cancer cachexia both cardiac and skeletal muscle suffer an important protein mobilization as a result of increased proteolysis. Administration of t…

  Authors: Sílvia Busquets, Maria T Figueras, Gemma Fuster, Vanessa Almendro, Rodrigo Moore-Carrasco, Elisabet Ametller, Josep M Argilés, Francisco J López-Soriano

  Source: Cancer research. 2004 Sep 15

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• Effects of CRF2R agonist on tumor growth and cachexia in mice implanted with Lewis lung carcinoma cells.

  Previous studies have demonstrated an effect of corticotropin-releasing factor 2 receptor (CRF2R) agonists in the maintenance of skeletal muscle mass.…

  Authors: Josep M Argilés, Maite Figueras, Elisabet Ametller, Gemma Fuster, Mireia Olivan, Cibely Cristine Fontes de Oliveira, Francisco J López-Soriano, Robert J Isfort, Sílvia Busquets

  Source: Muscle & nerve. 2008 Feb

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• Both oxidative and nitrosative stress are associated with muscle wasting in tumour-bearing rats.

  Reactive oxygen and nitrogen species (ROS and RNS) have been proposed as mechanisms of cancer-induced cachexia. In this study, we assessed using Weste…

  Authors: Esther Barreiro, Beatriz de la Puente, Sílvia Busquets, Francisco J López-Soriano, Joaquim Gea, Josep M Argilés

  Source: FEBS letters. 2005 Mar 14

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• PPARdelta mediates IL15 metabolic actions in myotubes: effects of hyperthermia.

  C2C12 cells exposed to hyperthermia (41 degrees C) experienced an increase in both protein synthesis and degradation. The addition of IL15 under hyper…

  Authors: Gemma Fuster, Sílvia Busquets, Maite Figueras, Elisabet Ametller, Cibely Cristine Fontes de Oliveira, Mireia Oliván, Paul A Grimaldi, Josep M Argilés, Francisco J López-Soriano

  Source: International journal of molecular medicine. 2009 Jul

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