1 to 10 of 186 literature results

• Prognostic relevance of increased Rac GTPase expression in prostate carcinomas.

  Rac proteins of the Rho-like GTPase family, including the ubiquitous Rac1, the hematopoiesis-specific Rac2, and the least-characterized Rac3 play a ma…

  Authors: R Engers, S Ziegler, M Mueller, A Walter, R Willers, H E Gabbert

  Source: Endocrine-related cancer. 2007 Jun

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• Pronounced thrombocytosis in transgenic mice expressing reduced levels of Mpl in platelets and terminally differentiated megakaryocytes.

  We generated mice expressing a full-length Mpl transgene under the control of a 2-kb Mpl promoter in an Mpl(-/-) background, effectively obtaining mic…

  Authors: Ralph Tiedt, Jörn Coers, Sandra Ziegler, Adrian Wiestner, Hui Hao-Shen, Caroline Bornmann, Johannes Schenkel, Svetlana Karakhanova, Frederic J de Sauvage, Carl W Jackson,…

  Source: Blood. 2009 Feb 19

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• PET/MRI system design.

  INTRODUCTION: The combination of clinical MRI and PET systems has received increased attention in recent years. In contrast to currently used PET/CT s…

  Authors: Gaspar Delso, Sibylle Ziegler

  Source: European journal of nuclear medicine and molecular imaging. 2009 Mar

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• Therapeutic targeting of apoptosis pathways in cancer.

  PURPOSE OF REVIEW: Anti-apoptotic mechanisms contribute to the development of cancer and the resistance of cancer cells to antitumor therapies. This r…

  Authors: David S Ziegler, Andrew L Kung

  Source: Current opinion in oncology. 2008 Jan

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• Matrix composition and community structure analysis of a novel bacterial pyrite leaching community.

  Here we describe a novel bacterial community that is embedded in a matrix of carbohydrates and bio/geochemical products of pyrite (FeS(2)) oxidation. …

  Authors: Sibylle Ziegler, Sonia Ackermann, Juraj Majzlan, Johannes Gescher

  Source: Environmental microbiology. 2009 Sep

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• Thioredoxin and thioredoxin reductase influence estrogen receptor alpha-mediated gene expression in human breast cancer cells.

  Accumulation of reactive oxygen species (ROS) in cells damages resident proteins, lipids, and DNA. In order to overcome the oxidative stress that occu…

  Authors: Abhi K Rao, Yvonne S Ziegler, Ian X McLeod, John R Yates, Ann M Nardulli

  Source: Journal of molecular endocrinology. 2009 Dec

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• Woodland-to-forest transition during prolonged drought in Minnesota after ca. AD 1300.

  Interactions among multiple causes of ecological perturbation, such as climate change and disturbance, can produce "ecological surprises." Here, we ex…

  Authors: Bryan Shuman, Anna K Henderson, Colin Plank, Ivanka Stefanova, Susy S Ziegler

  Source: Ecology. 2009 Oct

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• Interaction of estrogen receptor alpha with proliferating cell nuclear antigen.

  The ability of estrogen receptor alpha (ERalpha) to modulate gene expression is influenced by the recruitment of a host of co-regulatory proteins to t…

  Authors: Jennifer R Schultz-Norton, Vivian A Gabisi, Yvonne S Ziegler, Ian X McLeod, John R Yates, Ann M Nardulli

  Source: Nucleic acids research. 2007

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• A 2-kb c-mpl promoter fragment is sufficient to direct expression to the megakaryocytic lineage and sites of embryonic hematopoiesis in transgenic mice.

  Thrombopoietin receptor c-mpl is expressed on hematopoietic progenitors and cells of the megakaryocytic lineage. The c-mpl promoter may, therefore, be…

  Authors: Sandra Ziegler, Kurt Bürki, Radek C Skoda

  Source: Blood. 2002 Aug 1

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• Regulation: threat to converging technologies.

  This article discusses two competing principles underlying efforts to regulate technological developments converging at the nanoscale that are intende…

  Authors: Alan S Ziegler

  Source: Annals of the New York Academy of Sciences. 2006 Dec

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