1 to 10 of 33 literature results

• Forward genetic dissection of immunity to infection in the mouse.

  Forward genetics is an experimental approach in which gene mapping and positional cloning are used to elucidate the molecular mechanisms underlying ph…

  Authors: S M Vidal, D Malo, J-F Marquis, P Gros

  Source: Annual review of immunology. 2008

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• Methylenetetrahydrofolate reductase (MTHFR) deficiency enhances resistance against cytomegalovirus infection.

  Folates provide one-carbon units for nucleotide synthesis and methylation reactions. A common polymorphism in the MTHFR gene (677C --> T) results in r…

  Authors: N Fodil-Cornu, N Kozij, Q Wu, R Rozen, S M Vidal

  Source: Genes and immunity. 2009 Oct

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• Susceptibility to mouse cytomegalovirus is associated with deletion of an activating natural killer cell receptor of the C-type lectin superfamily.

  Cytomegalovirus is the leading cause of congenital viral disease and the most important opportunistic infection in immunocompromised patients. We have…

  Authors: S H Lee, S Girard, D Macina, M Busà, A Zafer, A Belouchi, P Gros, S M Vidal

  Source: Nature genetics. 2001 May

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• Complex genetic control of host susceptibility to coxsackievirus B3-induced myocarditis.

  The pathogenesis of viral myocarditis is a multifactorial process involving host genetics, viral genetics and the environment in which they interact. …

  Authors: M Aly, S Wiltshire, G Chahrour, J-C Loredo Osti, S M Vidal

  Source: Genes and immunity. 2007 Apr

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• NK cell recognition of mouse cytomegalovirus-infected cells.

  Abstract Natural killer (NK) cells and cytomegalovirus have been locked in an evolutionary arms race for millions of years in an attempt to overwhelm …

  Authors: S M Vidal, L L Lanier

  Source: Current topics in microbiology and immunology. 2006

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• Use of protein-interaction maps to formulate biological questions.

  Protein-interaction mapping approaches generate functional information for large numbers of genes that are predicted from complete genome sequences. T…

  Authors: S J Boulton, S Vincent, M Vidal

  Source: Current opinion in chemical biology. 2001 Feb

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• Pathological and genetic analysis of the degenerating muscle (dmu) mouse: a new allele of Scn8a.

  Here, we describe a novel spontaneous autosomal recessive mutation in the mouse that is characterized by skeletal and cardiac muscle degeneration. We …

  Authors: Y De Repentigny, P D Côté, M Pool, G Bernier, S Girard, S M Vidal, R Kothary

  Source: Human molecular genetics. 2001 Aug 15

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• Identification of potential interaction networks using sequence-based searches for conserved protein-protein interactions or "interologs".

  Protein interaction maps have provided insight into the relationships among the predicted proteins of model organisms for which a genome sequence is a…

  Authors: L R Matthews, P Vaglio, J Reboul, H Ge, B P Davis, J Garrels, S Vincent, M Vidal

  Source: Genome research. 2001 Dec

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• Atypical serological response marked by a lack of detectable anti-gp43 antibodies in a patient with disseminated paracoccidioidomycosis.

  Serological tests are frequently used to diagnosis paracoccidioidomycosis. A glycoprotein of 43 kDa is considered to be the main diagnostic antigen, b…

  Authors: Mônica S M Vidal, Gil Benard, Thales de Brito, Kátia C Dantas, Cristiane N Pereira, Francisco O S França, Ana M G da Silva, José E C Martins

  Source: Journal of clinical microbiology. 2005 Jun

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• Mammalian homologs of seven in absentia regulate DCC via the ubiquitin-proteasome pathway.

  DCC (deleted in colorectal cancer) is postulated to function as transmembrane receptor for the axon and cell guidance factor netrin-1. We report here …

  Authors: G Hu, S Zhang, M Vidal, J L Baer, T Xu, E R Fearon

  Source: Genes & development. 1997 Oct 15

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