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Authors: Russ B Altman
Source: Nature genetics. 2007 Apr
View Full TextPharmacogenomics requires the integration and analysis of genomic, molecular, cellular, and clinical data, and it thus offers a remarkable set of chal…
Authors: Russ B Altman, Teri E Klein
Source: Annual review of pharmacology and toxicology. 2002
View Full TextPharmGKB, the pharmacogenetics and pharmacogenomics knowledge base (www.pharmgkb.org) is a publicly available online resource dedicated to the dissemi…
Authors: Ryan P Owen, Russ B Altman, Teri E Klein
Source: Human mutation. 2008 Apr
View Full TextThe immense volume and rapid growth of human genomic data, especially single nucleotide polymorphisms (SNPs), present special challenges for both biom…
Authors: Zhen Lin, Russ B Altman
Source: American journal of human genetics. 2004 Nov
View Free Full TextThe use of capillary electrophoresis with fluorescently labeled nucleic acids revolutionized DNA sequencing, effectively fueling the genomic revolutio…
Authors: Somdeb Mitra, Inna V Shcherbakova, Russ B Altman, Michael Brenowitz, Alain Laederach
Source: Nucleic acids research. 2008 Jun
View Full TextThe Pharmacogenetics and Pharmacogenomics Knowledge Base (PharmGKB: http://www.pharmgkb.org) is devoted to disseminating primary data and knowledge in…
Authors: Katrin Sangkuhl, Dorit S Berlin, Russ B Altman, Teri E Klein
Source: Drug metabolism reviews. 2008
View Free Full TextThe outcome of drug therapy is often unpredictable, ranging from beneficial effects to lack of efficacy to serious adverse effects. Variations in sing…
Authors: Dan M Roden, Russ B Altman, Neal L Benowitz, David A Flockhart, Kathleen M Giacomini, Julie A Johnson, Ronald M Krauss, Howard L McLeod, Mark J Ratain, Mary V Relling,…
Source: Annals of internal medicine. 2006 Nov 21
View Full TextA fundamental task of pharmacogenetics is to collect and classify relationships between genes and drugs. Currently, this useful information has not be…
Authors: Jeffrey T Chang, Russ B Altman
Source: Pharmacogenetics. 2004 Sep
View Full TextAlternative splicing plays an important role in processes such as development, differentiation and cancer. With the recent increase in the estimates o…
Authors: Shuo Liu, Russ B Altman
Source: Nucleic acids research. 2003 Aug 15
View Full TextWe present a computational method that predicts a pathway of residues that mediate protein allosteric communication. The pathway is predicted using on…
Authors: Susan Tang, Jung-Chi Liao, Alexander R Dunn, Russ B Altman, James A Spudich, Jeanette P Schmidt
Source: Journal of molecular biology. 2007 Nov 9
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