1 to 8 of 8 literature results

• Regulatory networks define phenotypic classes of human stem cell lines.

  Stem cells are defined as self-renewing cell populations that can differentiate into multiple distinct cell types. However, hundreds of different huma…

  Authors: Franz-Josef Müller, Louise C Laurent, Dennis Kostka, Igor Ulitsky, Roy Williams, Christina Lu, In-Hyun Park, Mahendra S Rao, Ron Shamir, Philip H Schwartz,…

  Source: Nature. 2008 Sep 18

  View Free Full Text

• Molecular signature of MT1-MMP: transactivation of the downstream universal gene network in cancer.

  Invasion-promoting MT1-MMP is directly linked to tumorigenesis and metastasis. Our studies led us to identify those genes, the expression of which is …

  Authors: Dmitri V Rozanov, Alexei Y Savinov, Roy Williams, Kang Liu, Vladislav S Golubkov, Stan Krajewski, Alex Y Strongin

  Source: Cancer research. 2008 Jun 1

  View Free Full Text

• Ets2 is required for trophoblast stem cell self-renewal.

  The Ets2 transcription factor is essential for the development of the mouse placenta and for generating signals for embryonic mesoderm and axis format…

  Authors: Fang Wen, John A Tynan, Grace Cecena, Roy Williams, Jorge Múnera, George Mavrothalassitis, Robert G Oshima

  Source: Developmental biology. 2007 Dec 1

  View Free Full Text

• Type II estrogen binding site agonist: synthesis and biological evaluation of the enantiomers of methyl-para-hydroxyphenyllactate (MeHPLA).

  A high-affinity ligand for the type II estrogen binding site (EBS) was identified. Methyl para-hydroxyphenyllactate (MeHPLA) was observed to suppress …

  Authors: Lester Pretlow, Roy Williams, Mark Elliott

  Source: Chirality. 2003 Oct

  View Full Text

• Effects of altered corneal stiffness on native and postoperative LASIK corneal biomechanical behavior: A whole-eye finite element analysis.

  PURPOSE: To investigate the impact of corneal elasticity on corneal shape changes before and after simulated LASIK with and without consideration of w…

  Authors: Abhijit Sinha Roy, William J Dupps

  Source: Journal of refractive surgery (Thorofare, N.J. : 1995). 2009 Oct

  View Full Text

• Inflammatory proprotein convertase-matrix metalloproteinase proteolytic pathway in antigen-presenting cells as a step to autoimmune multiple sclerosis.

  Multiple sclerosis (MS) is a disease of the central nervous system with autoimmune etiology. Susceptibility to MS is linked to viral and bacterial inf…

  Authors: Sergey A Shiryaev, Albert G Remacle, Alexei Y Savinov, Andrei V Chernov, Piotr Cieplak, Ilian A Radichev, Roy Williams, Tatiana N Shiryaeva, Katarzyna Gawlik, Tatiana I Postnova,…

  Source: The Journal of biological chemistry. 2009 Oct 30

  View Full Text

• The ACTCellerate initiative: large-scale combinatorial cloning of novel human embryonic stem cell derivatives.

  Human embryonic stem cells offer a scalable and renewable source of all somatic cell types. Human embryonic progenitor (hEP) cells are partially diffe…

  Authors: Michael D West, R Geoffrey Sargent, Jeff Long, Colleen Brown, Jing Song Chu, Steven Kessler, Nikita Derugin, Janani Sampathkumar, Courtney Burrows, Homayoun Vaziri,…

  Source: Regenerative medicine. 2008 May

  View Full Text

• The degree of oligomerization of the H-NS nucleoid structuring protein is related to specific binding to DNA.

  At several E. coli promoters, initiation of transcription is repressed by a tight nucleoprotein complex formed by the assembly of the H-NS protein. In…

  Authors: Cyril Badaut, Roy Williams, Veronique Arluison, Emeline Bouffartigues, Bruno Robert, Henri Buc, Sylvie Rimsky

  Source: The Journal of biological chemistry. 2002 Nov 1

  View Full Text