1 to 10 of 62 literature results

• T-cell modulation combined with intratumoral CpG cures lymphoma in a mouse model without the need for chemotherapy.

  We have previously shown that intratumoral injection of CpG oligodeoxynucleotide plus systemic chemotherapy can induce a T-cell immune response agains…

  Authors: Roch Houot, Ronald Levy

  Source: Blood. 2009 Apr 9

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• Generation of CD8+ T cell-mediated immunity against idiotype-negative lymphoma escapees.

  We investigated the ability of CpG-oligodeoxynucleotide to generate an anti-tumor CD8+ T-cell immune response and to synergize with passive antibody t…

  Authors: Bindu Varghese, Adam Widman, James Do, Behnaz Taidi, Debra K Czerwinski, John Timmerman, Shoshana Levy, Ronald Levy

  Source: Blood. 2009 Nov 12

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• Immunotransplantation preferentially expands T-effector cells over T-regulatory cells and cures large lymphoma tumors.

  Ex vivo-expanded tumor-infiltrating lymphocytes infused into lymphodepleted recipients has clear antitumor efficacy. More practical sources of such an…

  Authors: Joshua D Brody, Matthew J Goldstein, Debra K Czerwinski, Ronald Levy

  Source: Blood. 2009 Jan 1

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• Anti-idiotype antibody response after vaccination correlates with better overall survival in follicular lymphoma.

  Previous studies demonstrated that vaccination-induced tumor-specific immune response is associated with superior clinical outcome in patients with fo…

  Authors: Weiyun Z Ai, Robert Tibshirani, Behnaz Taidi, Debra Czerwinski, Ronald Levy

  Source: Blood. 2009 Jun 4

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• Humoral immune response and immunoglobulin G Fc receptor genotype are associated with better clinical outcome following idiotype vaccination in follicular lymphoma patients regardless of their response to induction chemotherapy.

  We have reported that anti-idiotype antibody response and FcgammaRIIIa 158 valine/valine (V/V) genotype both correlate with better outcome in a group …

  Authors: Wen-Kai Weng, Debra Czerwinski, Ronald Levy

  Source: Blood. 2007 Feb 1

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• Cell-free production of scFv fusion proteins: an efficient approach for personalized lymphoma vaccines.

  The unique immunoglobulin (Ig) idiotype on the surface of each B-cell lymphoma represents an ideal tumor-specific antigen for use as a therapeutic vac…

  Authors: Gregory Kanter, Junhao Yang, Alexei Voloshin, Shoshana Levy, James R Swartz, Ronald Levy

  Source: Blood. 2007 Apr 15

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• A pluripotency signature predicts histologic transformation and influences survival in follicular lymphoma patients.

  Histologic transformation (HT) of follicular lymphoma to diffuse large B-cell lymphoma (DLBCL-t) is associated with accelerated disease course and dra…

  Authors: Andrew J Gentles, Ash A Alizadeh, Su-In Lee, June H Myklebust, Catherine M Shachaf, Babak Shahbaba, Ronald Levy, Daphne Koller, Sylvia K Plevritis

  Source: Blood. 2009 Oct 8

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• Therapeutic vaccination against murine lymphoma by intratumoral injection of naive dendritic cells.

  Dendritic cells are potent antigen-presenting cells that can induce both immune responses and tolerance depending on their state of activation. Immuno…

  Authors: Wenru Song, Ronald Levy

  Source: Cancer research. 2005 Jul 1

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• Therapeutic vaccination against murine lymphoma by intratumoral injection of recombinant fowlpox virus encoding CD40 ligand.

  The interaction between CD40 ligand (CD40L, CD154) and its receptor CD40 on antigen-presenting cells is essential for the initiation of cell-mediated …

  Authors: Aichun Liu, Alice Guardino, Lek Chinsangaram, Matthew J Goldstein, Dennis Panicali, Ronald Levy

  Source: Cancer research. 2007 Jul 15

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• Altered B-cell receptor signaling kinetics distinguish human follicular lymphoma B cells from tumor-infiltrating nonmalignant B cells.

  The B-cell receptor (BCR) transmits life and death signals throughout B-cell development, and altered BCR signaling may be required for survival of B-…

  Authors: Jonathan M Irish, Debra K Czerwinski, Garry P Nolan, Ronald Levy

  Source: Blood. 2006 Nov 1

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