1 to 4 of 4 literature results

• Dopamine D2 receptor knockout mice develop features of Parkinson disease.

  OBJECTIVE: This study questions whether increased dopamine (DA) turnover in nigral neurons leads to formation of Lewy bodies (LBs), the characteristic…

  Authors: Rogan B Tinsley, Chris R Bye, Clare L Parish, Angela Tziotis-Vais, Sonia George, Janetta G Culvenor, Qiao-Xin Li, Colin L Masters, David I Finkelstein, Malcolm K Horne

  Source: Annals of neurology. 2009 Oct

  View Full Text

• Adult neural stem/progenitor cells reduce NMDA-induced excitotoxicity via the novel neuroprotective peptide pentinin.

  Although the potential of adult neural stem cells to repair damage via cell replacement has been widely reported, the ability of endogenous stem cells…

  Authors: Jonas Faijerson, Annika Thorsell, Joakim Strandberg, Eric Hanse, Mats Sandberg, Peter S Eriksson, Rogan B Tinsley

  Source: Journal of neurochemistry. 2009 May

  View Full Text

• Use of engineered peripheral nerve autografts for spinal cord repair.

  We developed a clinically compatible protocol for the production of engineered tissue for grafting into the injured spinal cord. We used autologous ti…

  Authors: Rogan B Tinsley, Shu-Hua Zhang, Shi-Qing Feng, Robert A Rush, Ian A Ferguson

  Source: Neuroreport. 2006 Feb 27

  View Full Text

• Improved non-viral transfection of glial and adult neural stem cell lines and of primary astrocytes by combining agents with complementary modes of action.

  BACKGROUND: Rational design of gene vectors for therapeutic applications requires understanding of transfection mechanisms. In this study, multiple tr…

  Authors: Rogan B Tinsley, Melanie J Vesey, Shahram Barati, Robert A Rush, Ian A Ferguson

  Source: The journal of gene medicine. 2004 Sep

  View Full Text