1 to 10 of 20 literature results

• Antimicrobial peptides and self-DNA in autoimmune skin inflammation.

  Toll-like receptor (TLR)-mediated detection of viral nucleic acids and production of type I interferons (IFNs) by plasmacytoid dendritic cells (pDCs) …

  Authors: Michel Gilliet, Roberto Lande

  Source: Current opinion in immunology. 2008 Aug

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• Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide.

  Plasmacytoid dendritic cells (pDCs) sense viral and microbial DNA through endosomal Toll-like receptors to produce type 1 interferons. pDCs do not nor…

  Authors: Roberto Lande, Josh Gregorio, Valeria Facchinetti, Bithi Chatterjee, Yi-Hong Wang, Bernhard Homey, Wei Cao, Yui-Hsi Wang, Bing Su, Frank O Nestle,…

  Source: Nature. 2007 Oct 4

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• Plasmacytoid dendritic cells: key players in the initiation and regulation of immune responses.

  Plasmacytoid dendritic cells (pDCs) are a rare population of circulating cells that selectively express Toll-like receptors (TLR)7 and TLR9 and have t…

  Authors: Roberto Lande, Michel Gilliet

  Source: Annals of the New York Academy of Sciences. 2010 Jan

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• IFN-beta modulates the response to TLR stimulation in human DC: involvement of IFN regulatory factor-1 (IRF-1) in IL-27 gene expression.

  Type I IFN are cytokines which play a central role in host resistance to viral or microbial infections and are important components linking innate and…

  Authors: Maria Elena Remoli, Valérie Gafa, Elena Giacomini, Martina Severa, Roberto Lande, Eliana M Coccia

  Source: European journal of immunology. 2007 Dec

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• Plasmacytoid dendritic cells in multiple sclerosis: intracerebral recruitment and impaired maturation in response to interferon-beta.

  The roles of plasmacytoid dendritic cells (pDCs) and their response to interferon (IFN)-beta therapy in multiple sclerosis (MS) patients are poorly un…

  Authors: Roberto Lande, Valérie Gafa, Barbara Serafini, Elena Giacomini, Andrea Visconti, Maria Elena Remoli, Martina Severa, Marc Parmentier, Giovanni Ristori, Marco Salvetti,…

  Source: Journal of neuropathology and experimental neurology. 2008 May

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• NF-{kappa}B is required for STAT-4 expression during dendritic cell maturation.

  The transcription factor STAT-4 plays a pivotal role in the IL-12-mediated development of naive CD4+ T cells into the Th1 phenotype. Initially thought…

  Authors: Maria Elena Remoli, Josiane Ragimbeau, Elena Giacomini, Valerie Gafa, Martina Severa, Roberto Lande, Sandra Pellegrini, Eliana M Coccia

  Source: Journal of leukocyte biology. 2007 Jan

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• Differential responsiveness to IFN-alpha and IFN-beta of human mature DC through modulation of IFNAR expression.

  In human monocyte-derived dendritic cells (DC), infection with Mycobacterium tuberculosis and viruses or stimulation with Toll-like receptor type 3 an…

  Authors: Martina Severa, Maria Elena Remoli, Elena Giacomini, Josiane Ragimbeau, Roberto Lande, Gilles Uzé, Sandra Pellegrini, Eliana M Coccia

  Source: Journal of leukocyte biology. 2006 Jun

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• Astrocytes produce dendritic cell-attracting chemokines in vitro and in multiple sclerosis lesions.

  As a result of their close association with the blood-brain barrier, astrocytes play an important role in regulating the homing of different leukocyte…

  Authors: Elena Ambrosini, Maria Elena Remoli, Elena Giacomini, Barbara Rosicarelli, Barbara Serafini, Roberto Lande, Francesca Aloisi, Eliana Marina Coccia

  Source: Journal of neuropathology and experimental neurology. 2005 Aug

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• Infection of human dendritic cells with a Mycobacterium tuberculosis sigE mutant stimulates production of high levels of interleukin-10 but low levels of CXCL10: impact on the T-cell response.

  The Mycobacterium tuberculosis genome encodes 13 sigma factors. We have previously shown that mutations in some of these transcriptional activators re…

  Authors: Elena Giacomini, Ambar Sotolongo, Elisabetta Iona, Martina Severa, Maria Elena Remoli, Valerie Gafa, Roberto Lande, Lanfranco Fattorini, Issar Smith, Riccardo Manganelli,…

  Source: Infection and immunity. 2006 Jun

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• Human dendritic cells following Aspergillus fumigatus infection express the CCR7 receptor and a differential pattern of interleukin-12 (IL-12), IL-23, and IL-27 cytokines, which lead to a Th1 response.

  Aspergillus fumigatus is the most prevalent airborne fungal pathogen and causes fatal invasive aspergillosis in immunocompromised patients. Given the …

  Authors: Valérie Gafa, Roberto Lande, Maria Cristina Gagliardi, Martina Severa, Elena Giacomini, Maria Elena Remoli, Roberto Nisini, Carlo Ramoni, Paolo Di Francesco, Delphine Aldebert,…

  Source: Infection and immunity. 2006 Mar

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