1 to 3 of 3 literature results

• TORCs: transducers of regulated CREB activity.

  The cAMP responsive factor CREB stimulates gene expression, following its phosphorylation at Ser133, via recruitment of the coactivator CBP. In certai…

  Authors: Michael D Conkright, Gianluca Canettieri, Robert Screaton, Ernesto Guzman, Loren Miraglia, John B Hogenesch, Marc Montminy

  Source: Molecular cell. 2003 Aug

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• The coactivator CRTC1 promotes cell proliferation and transformation via AP-1.

  Regulation of gene expression in response to mitogenic stimuli is a critical aspect underlying many forms of human cancers. The AP-1 complex mediates …

  Authors: Gianluca Canettieri, Sonia Coni, Michele Della Guardia, Valentina Nocerino, Laura Antonucci, Laura Di Magno, Robert Screaton, Isabella Screpanti, Giuseppe Giannini, Alberto Gulino

  Source: Proceedings of the National Academy of Sciences of the United States of America. 2009 Feb 3

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• TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism.

  During fasting, increased concentrations of circulating catecholamines promote the mobilization of lipid stores from adipose tissue in part by phospho…

  Authors: Ling Qi, Jose E Heredia, Judith Y Altarejos, Robert Screaton, Naomi Goebel, Sherry Niessen, Ian X Macleod, Chong Wee Liew, Rohit N Kulkarni, James Bain,…

  Source: Science (New York, N.Y.). 2006 Jun 23

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