1 to 10 of 109 literature results

• Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis.

  The TMPRSS2-ERG fusion, present in approximately 50% of prostate cancers, is less common in prostatic intraepithelial neoplasia (PIN), raising questio…

  Authors: Jennifer C King, Jin Xu, John Wongvipat, Haley Hieronymus, Brett S Carver, David H Leung, Barry S Taylor, Chris Sander, Robert D Cardiff, Suzana S Couto,…

  Source: Nature genetics. 2009 May

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• Pathologists needed to cope with mutant mice.

  Authors: Robert D Cardiff

  Source: Nature. 2007 May 31

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• Selective evolution of stromal mesenchyme with p53 loss in response to epithelial tumorigenesis.

  Our understanding of cancer has largely come from the analysis of aberrations within the tumor cell population. Yet it is increasingly clear that the …

  Authors: Reginald Hill, Yurong Song, Robert D Cardiff, Terry Van Dyke

  Source: Cell. 2005 Dec 16

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• Mouse mammary tumor biology: a short history.

  For over a century, mouse mammary tumor biology and the associated Mouse mammary tumor virus (MMTV) have served as the foundation for experimental can…

  Authors: Robert D Cardiff, Nicholas Kenney

  Source: Advances in cancer research. 2007

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• MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer.

  Hepatocellular carcinoma is generally refractory to clinical treatment. Here, we report that inactivation of the MYC oncogene is sufficient to induce …

  Authors: Catherine M Shachaf, Andrew M Kopelman, Constadina Arvanitis, Asa Karlsson, Shelly Beer, Stefanie Mandl, Michael H Bachmann, Alexander D Borowsky, Boris Ruebner, Robert D Cardiff,…

  Source: Nature. 2004 Oct 28

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• Somatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesis.

  Metastatic disease is the primary cause of death in breast cancer, the most common malignancy in Western women. Loss of E-cadherin is associated with …

  Authors: Patrick W B Derksen, Xiaoling Liu, Francis Saridin, Hanneke van der Gulden, John Zevenhoven, Bastiaan Evers, Judy R van Beijnum, Arjan W Griffioen, Jacqueline Vink, Paul Krimpenfort,…

  Source: Cancer cell. 2006 Nov

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• Phosphatase and tensin homologue deleted on chromosome 10 deficiency accelerates tumor induction in a mouse model of ErbB-2 mammary tumorigenesis.

  Loss of the tumor suppressor phosphatase and tensin homologue deleted on chromosome 10 (PTEN) and amplification or elevated expression of ErbB-2 are b…

  Authors: Nathalie Dourdin, Babette Schade, Robert Lesurf, Michael Hallett, Robert J Munn, Robert D Cardiff, William J Muller

  Source: Cancer research. 2008 Apr 1

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• The transcriptional repressor Snail promotes mammary tumor recurrence.

  Breast cancer recurrence is a fundamental clinical manifestation of tumor progression and represents the principal cause of death from this disease. U…

  Authors: Susan E Moody, Denise Perez, Tien-chi Pan, Christopher J Sarkisian, Carla P Portocarrero, Christopher J Sterner, Kathleen L Notorfrancesco, Robert D Cardiff, Lewis A Chodosh

  Source: Cancer cell. 2005 Sep

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• Effect of c-neu/ ErbB2 expression levels on estrogen receptor alpha-dependent proliferation in mammary epithelial cells: implications for breast cancer biology.

  Mammary development and tumorigenesis are profoundly influenced by signaling pathways under the control of c-erbB2/c-neu and estrogen receptor alpha (…

  Authors: Gopalan Shyamala, Yu-Chien Chou, Robert D Cardiff, Elizabeth Vargis

  Source: Cancer research. 2006 Nov 1

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• T-cadherin supports angiogenesis and adiponectin association with the vasculature in a mouse mammary tumor model.

  T-cadherin delineates endothelial, myoepithelial, and ductal epithelial cells in the normal mouse mammary gland, and becomes progressively restricted …

  Authors: Lionel W Hebbard, Michèle Garlatti, Lawrence J T Young, Robert D Cardiff, Robert G Oshima, Barbara Ranscht

  Source: Cancer research. 2008 Mar 1

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