Click on one of these terms to refine your search
1 to 10 of 27 literature results
Protein tyrosine phosphatases (PTPs) are important regulators of many cellular functions and a growing number of PTPs have been implicated in human di…
Authors: Torkel Vang, Ana V Miletic, Yutaka Arimura, Lutz Tautz, Robert C Rickert, Tomas Mustelin
Source: Annual review of immunology. 2008
View Full TextThe proliferation of antigen-specific lymphocytes and resulting clonal expansion are essential for adaptive immunity. We report here that B cell-speci…
Authors: Joseph Cantor, Cecille D Browne, Raphael Ruppert, Chloé C Féral, Reinhard Fässler, Robert C Rickert, Mark H Ginsberg
Source: Nature immunology. 2009 Apr
View Free Full TextAnergy is a critical physiologic mechanism to sensor self-reactive B cells. However, a biochemical understanding of how anergy is achieved and maintai…
Authors: Cecille D Browne, Christopher J Del Nagro, Matthew H Cato, Hart S Dengler, Robert C Rickert
Source: Immunity. 2009 Nov 20
View Full TextThe transcription factors Foxo1, Foxo3 and Foxo4 modulate cell fate 'decisions' in diverse systems. Here we show that Foxo1-dependent gene expression …
Authors: Hart S Dengler, Gisele V Baracho, Sidne A Omori, Shane Bruckner, Karen C Arden, Diego H Castrillon, Ronald A DePinho, Robert C Rickert
Source: Nature immunology. 2008 Dec
View Free Full TextComplement is an essential innate immune mechanism that recognizes and eradicates microbes and associated toxins. In addition, complement receptors (C…
Authors: Robert C Rickert
Source: Current opinion in immunology. 2005 Jun
View Full TextPhosphoinositide 3-kinase (PI3K) and phosphatase and tensin homolog (PTEN) phosphatase serve essential functions in the regulation of cell growth, dif…
Authors: Amy N Anzelon, Hong Wu, Robert C Rickert
Source: Nature immunology. 2003 Mar
View Full TextClass-switch recombination (CSR) is essential for humoral immunity. However, the regulation of CSR is not completely understood. Here we demonstrate t…
Authors: Sidne A Omori, Matthew H Cato, Amy Anzelon-Mills, Kamal D Puri, Miriam Shapiro-Shelef, Kathryn Calame, Robert C Rickert
Source: Immunity. 2006 Oct
View Full TextExpression of B cell-activating factor (BAFF), a critical B cell survival factor, is elevated in autoimmune and lymphoproliferative disorders. Mice ov…
Authors: Thomas Enzler, Giuseppina Bonizzi, Gregg J Silverman, Dennis C Otero, George F Widhopf, Amy Anzelon-Mills, Robert C Rickert, Michael Karin
Source: Immunity. 2006 Sep
View Full TextStat proteins are latent cytoplasmic transcription factors that are crucial in many aspects of mammalian development. In the immune system, Stat3 has …
Authors: Jamie L Fornek, Lorraine T Tygrett, Thomas J Waldschmidt, Valeria Poli, Robert C Rickert, Geoffrey S Kansas
Source: Blood. 2006 Feb 1
View Free Full TextTNF receptor (TNFR) superfamily members, CD40, and BAFFR play critical roles in B cell survival and differentiation. Genetic deficiency in a novel ada…
Authors: Youcun Qian, Jinzhong Qin, Grace Cui, Mayumi Naramura, E Charles Snow, Carl F Ware, Robert L Fairchild, Sidne A Omori, Robert C Rickert, Martin Scott,…
Source: Immunity. 2004 Oct
View Full Text