1 to 9 of 9 literature results

• Ultrasound and microbubble-targeted delivery of macromolecules is regulated by induction of endocytosis and pore formation.

  Contrast microbubbles in combination with ultrasound (US) are promising vehicles for local drug and gene delivery. However, the exact mechanisms behin…

  Authors: Bernadet D M Meijering, Lynda J M Juffermans, Annemieke van Wamel, Rob H Henning, Inge S Zuhorn, Marcia Emmer, Amanda M G Versteilen, Walter J Paulus, Wiek H van Gilst, Klazina Kooiman,…

  Source: Circulation research. 2009 Mar 13

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• Vascular contraction and preeclampsia: downregulation of the Angiotensin receptor 1 by hemopexin in vitro.

  During normal pregnancy, in contrast to preeclampsia, plasma hemopexin activity is increased together with a decreased vascular angiotensin II recepto…

  Authors: Winston W Bakker, Rob H Henning, Willem J van Son, Maria G van Pampus, Jan G Aarnoudse, Klary E Niezen-Koning, Theo Borghuis, Rianne M Jongman, Harry van Goor, Klaas Poelstra,…

  Source: Hypertension. 2009 Jun

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• Caveolae and endothelial dysfunction: filling the caves in cardiovascular disease.

  Discovery in the early 1990s of caveolin-1, the structural protein responsible for maintaining the ohm shape of caveolae, greatly enhanced investigati…

  Authors: Ying Xu, Hendrik Buikema, Wiek H van Gilst, Rob H Henning

  Source: European journal of pharmacology. 2008 May 13

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• Altered myogenic constriction and endothelium-derived hyperpolarizing factor-mediated relaxation in small mesenteric arteries of hypertensive subtotally nephrectomized rats.

  OBJECTIVES: Chronic renal failure (CRF) is associated with altered systemic arterial tone and hypertension. Myogenic constriction and endothelium-deri…

  Authors: Simone Vettoretti, Peter Ochodnicky, Hendrik Buikema, Rob H Henning, C Alex Kluppel, Dick de Zeeuw, Richard P E van Dokkum

  Source: Journal of hypertension. 2006 Nov

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• Enhanced myogenic constriction of mesenteric artery in heart failure relates to decreased smooth muscle cell caveolae numbers and altered AT1- and epidermal growth factor-receptor function.

  AIMS: We previously showed that enhanced myogenic constriction (MC) of peripheral resistance arteries involves active AT(1) receptors in chronic heart…

  Authors: Ying Xu, Rob H Henning, Maria Sandovici, Johannes J van der Want, Wiek H van Gilst, Hendrik Buikema

  Source: European journal of heart failure : journal of the Working Group on Heart Failure of the European Society of Cardiology. 2009 Mar

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• Rat abdominal aorta stenting: a new and reliable small animal model for in-stent restenosis.

  BACKGROUND: A high throughput animal model may enhance pathophysiological studies to mechanisms of in-stent restenosis (ISR). More and appropriate ant…

  Authors: Bas Langeveld, Anton J M Roks, René A Tio, Ad J van Boven, Johannes J L van der Want, Rob H Henning, Heleen M M van Beusekom, Willem J van der Giessen, Felix Zijlstra, Wiek H van Gilst

  Source: Journal of vascular research. 2004 Sep-Oct

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• Protective role of endothelial nitric oxide synthase.

  Nitric oxide is a versatile molecule, with its actions ranging from haemodynamic regulation to anti-proliferative effects on vascular smooth muscle ce…

  Authors: Ester W J A Albrecht, Coen A Stegeman, Peter Heeringa, Rob H Henning, Harry van Goor

  Source: The Journal of pathology. 2003 Jan

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• Myocardial infarction enhances progressive renal damage in an experimental model for cardio-renal interaction.

  Studied were the effects of myocardial infarction (MI) on mild renal function loss in unilateral nephrectomized (UnX) rats. UnX was performed, followe…

  Authors: Richard P E van Dokkum, Wouter B A Eijkelkamp, Alex C A Kluppel, Rob H Henning, Harry van Goor, Marin Citgez, Willemijn A K M Windt, Dirk J van Veldhuisen, Pieter A de Graeff, Dick de Zeeuw

  Source: Journal of the American Society of Nephrology : JASN. 2004 Dec

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• Enhanced responses of blood pressure, renal function, and aldosterone to angiotensin I in the DD genotype are blunted by low sodium intake.

  Angiotensin-converting enzyme (ACE) activity is increased in the DD genotype, but the functional significance for renal function is unknown. Blunted r…

  Authors: Frank G H van der Kleij, Paul E de Jong, Rob H Henning, Dick de Zeeuw, Gerjan Navis

  Source: Journal of the American Society of Nephrology : JASN. 2002 Apr

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