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Daxx is a nuclear protein that localizes to PML oncogenic domains, sensitizes cells to apoptosis, and functions as a transcriptional repressor. We fou…
Authors: Rhonda Croxton, Lorena A Puto, Ian de Belle, Michael Thomas, Seiji Torii, Farid Hanaii, Michael Cuddy, John C Reed
Source: Cancer research. 2006 Sep 15
View Full TextTumor necrosis factor-related apoptosis-inducing ligand (TRAIL or Apo2L) has been shown to induce apoptosis specifically in cancer cells while sparing…
Authors: Marc L Hyer, Rhonda Croxton, Maryla Krajewska, Stanislaw Krajewski, Christina L Kress, Meiling Lu, Nanjoo Suh, Michael B Sporn, Vincent L Cryns, Juan M Zapata,…
Source: Cancer research. 2005 Jun 1
View Full TextE2F1 is a potent inducer of apoptosis whereas its relative, E2F4, generally does not promote cell death. Other work from our laboratory has demonstrat…
Authors: Rhonda Croxton, Yihong Ma, W Douglas Cress
Source: Oncogene. 2002 Feb 28
View Full TextE2F1 induces apoptosis via both p53-dependent and p53-independent mechanisms. The direct targets in the p53-independent pathway remain enigmatic; howe…
Authors: Rhonda Croxton, Yihong Ma, Lanxi Song, Eric B Haura, W Douglas Cress
Source: Oncogene. 2002 Feb 21
View Full TextThe E2F pathway has been proposed to regulate genes involved in the transition from quiescence into DNA synthesis. However, this hypothesis has not be…
Authors: Yihong Ma, Rhonda Croxton, Ronnie L Moorer, W Douglas Cress
Source: Archives of biochemistry and biophysics. 2002 Mar 15
View Full TextIschemia-reperfusion (IR) injury induces endoplasmic reticulum (ER) stress and cell death. Bax Inhibitor-1 (BI-1) is an evolutionarily conserved ER pr…
Authors: Béatrice Bailly-Maitre, Constantino Fondevila, Fady Kaldas, Nathalie Droin, Fréderic Luciano, Jean-Ehrland Ricci, Rhonda Croxton, Maryla Krajewska, Juan M Zapata, Jerzy W Kupiec-Weglinski,…
Source: Proceedings of the National Academy of Sciences of the United States of America. 2006 Feb 21
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