1 to 10 of 26 literature results

• The original Pathologische Anatomie Leiden-Endothelium monoclonal antibody recognizes a vascular endothelial growth factor binding site within neuropilin-1.

  For two decades, the antigen recognized by the Pathologische Anatomie Leiden-Endothelium (PAL-E) monoclonal antibody, a standard vascular endothelial …

  Authors: Diana E Jaalouk, Michael G Ozawa, Jessica Sun, Johanna Lahdenranta, Reinier O Schlingemann, Renata Pasqualini, Wadih Arap

  Source: Cancer research. 2007 Oct 15

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• Aminopeptidase A is a functional target in angiogenic blood vessels.

  We show that a membrane-associated protease, aminopeptidase A (APA), is upregulated and enzymatically active in blood vessels of human tumors. To gain…

  Authors: Serena Marchiò, Johanna Lahdenranta, Reinier O Schlingemann, Donatella Valdembri, Pieter Wesseling, Marco A Arap, Amin Hajitou, Michael G Ozawa, Martin Trepel, Ricardo J Giordano,…

  Source: Cancer cell. 2004 Feb

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• Selective loss of inner retinal layer thickness in type 1 diabetic patients with minimal diabetic retinopathy.

  PURPOSE: To determine whether type 1 diabetes preferentially affects the inner retinal layers by comparing the thickness of six retinal layers in type…

  Authors: Hille W van Dijk, Pauline H B Kok, Mona Garvin, Milan Sonka, J Hans Devries, Robert P J Michels, Mirjam E J van Velthoven, Reinier O Schlingemann, Frank D Verbraak, Michael D Abràmoff

  Source: Investigative ophthalmology & visual science. 2009 Jul

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• Effect of VEGF-A on expression of profibrotic growth factor and extracellular matrix genes in the retina.

  PURPOSE: Vascular endothelial growth factor-A (VEGF) causes increased vascular permeability and leukocyte adhesion in preclinical diabetic retinopathy…

  Authors: Esther J Kuiper, John M Hughes, Rob J Van Geest, Ilse M C Vogels, Roel Goldschmeding, Cornelis J F Van Noorden, Reinier O Schlingemann, Ingeborg Klaassen

  Source: Investigative ophthalmology & visual science. 2007 Sep

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• START Trial: a pilot study on STimulation of ARTeriogenesis using subcutaneous application of granulocyte-macrophage colony-stimulating factor as a new treatment for peripheral vascular disease.

  BACKGROUND: Granulocyte-macrophage colony-stimulating factor (GM-CSF) was recently shown to increase collateral flow index in patients with coronary a…

  Authors: Niels van Royen, Stephan H Schirmer, Bektas Atasever, Casper Y H Behrens, Dirk Ubbink, Eva E Buschmann, Michiel Voskuil, Pieter Bot, Imo Hoefer, Reinier O Schlingemann,…

  Source: Circulation. 2005 Aug 16

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• Diabetes changes ionotropic glutamate receptor subunit expression level in the human retina.

  Early diabetic retinopathy is characterized by changes in subtle visual functions such as contrast sensitivity and dark adaptation. The outcome of sev…

  Authors: Ana R Santiago, John M Hughes, Willem Kamphuis, Reinier O Schlingemann, António F Ambrósio

  Source: Brain research. 2008 Mar 10

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• Vascular endothelial growth factor overexpression in ischemic skeletal muscle enhances myoglobin expression in vivo.

  Therapeutic angiogenesis using vascular endothelial growth factor (VEGF) is considered a promising new therapy for patients with arterial obstructive …

  Authors: Vincent van Weel, Martine M L Deckers, Jos M Grimbergen, Kees J M van Leuven, JanWillem H P Lardenoye, Reinier O Schlingemann, Geerten P van Nieuw Amerongen, J Hajo van Bockel, Victor W M van Hinsbergh, Paul H A Quax

  Source: Circulation research. 2004 Jul 9

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• Altered expression of genes related to blood-retina barrier disruption in streptozotocin-induced diabetes.

  Disruption of the blood-retina barrier (BRB) is an early phenomenon in preclinical diabetic retinopathy (PCDR). Two vascular permeability pathways may…

  Authors: Ingeborg Klaassen, John M Hughes, Ilse M C Vogels, Casper G Schalkwijk, Cornelis J F Van Noorden, Reinier O Schlingemann

  Source: Experimental eye research. 2009 Jun 15

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• Connective tissue growth factor is increased in plasma of type 1 diabetic patients with nephropathy.

  OBJECTIVE: Connective tissue growth factor (CTGF) is strongly upregulated in fibrotic disorders and has been hypothesized to play a role in the develo…

  Authors: Peggy Roestenberg, Frans A van Nieuwenhoven, Lotte Wieten, Peter Boer, Theo Diekman, Anna M Tiller, Wilmar M Wiersinga, Noelynn Oliver, William Usinger, Stephen Weitz,…

  Source: Diabetes care. 2004 May

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• Association of connective tissue growth factor with fibrosis in vitreoretinal disorders in the human eye.

  OBJECTIVE: To investigate the expression of the profibrotic connective tissue growth factor (CTGF) in relation to severity of intraocular fibrosis and…

  Authors: Esther J Kuiper, Marc D de Smet, Jan C van Meurs, H Stevie Tan, Michael W T Tanck, Noelynn Oliver, Frans A van Nieuwenhoven, Roel Goldschmeding, Reinier O Schlingemann

  Source: Archives of ophthalmology. 2006 Oct

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