1 to 10 of 75 literature results

• A key role for CCR7 in establishing central and peripheral tolerance.

  Early studies identified the CC-chemokine receptor (CCR)7 as an important homing molecule controlling the lymph node entry of naive T cells through hi…

  Authors: Tim Worbs, Reinhold Förster

  Source: Trends in immunology. 2007 Jun

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• Rapid leukocyte migration by integrin-independent flowing and squeezing.

  All metazoan cells carry transmembrane receptors of the integrin family, which couple the contractile force of the actomyosin cytoskeleton to the extr…

  Authors: Tim Lämmermann, Bernhard L Bader, Susan J Monkley, Tim Worbs, Roland Wedlich-Söldner, Karin Hirsch, Markus Keller, Reinhold Förster, David R Critchley, Reinhard Fässler,…

  Source: Nature. 2008 May 1

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• The peritoneal micromilieu commits B cells to home to body cavities and the small intestine.

  The distinct combination of homing receptors such as selectins, chemokine receptors, and integrins directs the migration of lymphocytes throughout the…

  Authors: Simon Berberich, Reinhold Förster, Oliver Pabst

  Source: Blood. 2007 Jun 1

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• Factors governing the intranodal migration behavior of T lymphocytes.

  With the advent of two-photon microscopic imaging, the last few years have witnessed remarkable progress regarding our understanding of the movement b…

  Authors: Tim Worbs, Günter Bernhardt, Reinhold Förster

  Source: Immunological reviews. 2008 Feb

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• Homeostatic chemokines in development, plasticity, and functional organization of the intestinal immune system.

  In the past decade accumulating evidence supported the view that the immune system should be regarded as trust consisting of several branches. In this…

  Authors: Reinhold Förster, Oliver Pabst, Günter Bernhardt

  Source: Seminars in immunology. 2008 Jun

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• Impaired responsiveness to T-cell receptor stimulation and defective negative selection of thymocytes in CCR7-deficient mice.

  The chemokine receptor CCR7 has been implicated in maintenance of thymus morphology and establishment of tolerance to self-antigens. In this study, we…

  Authors: Ana C M Davalos-Misslitz, Tim Worbs, Stefanie Willenzon, Günter Bernhardt, Reinhold Förster

  Source: Blood. 2007 Dec 15

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• T cell migration dynamics within lymph nodes during steady state: an overview of extracellular and intracellular factors influencing the basal intranodal T cell motility.

  Naive T lymphocytes continuously recirculate through secondary lymphoid organs such as lymph nodes until they are eventually activated by recognizing …

  Authors: Tim Worbs, Reinhold Förster

  Source: Current topics in microbiology and immunology. 2009

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• Cytohesin-1 controls the activation of RhoA and modulates integrin-dependent adhesion and migration of dendritic cells.

  Adhesion and motility of mammalian leukocytes are essential requirements for innate and adaptive immune defense mechanisms. We show here that the guan…

  Authors: Thomas Quast, Barbara Tappertzhofen, Cora Schild, Jessica Grell, Niklas Czeloth, Reinhold Förster, Ronen Alon, Line Fraemohs, Katrin Dreck, Christian Weber,…

  Source: Blood. 2009 Jun 4

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• Balanced responsiveness to chemoattractants from adjacent zones determines B-cell position.

  B lymphocytes re-circulate between B-cell-rich compartments (follicles or B zones) in secondary lymphoid organs, surveying for antigen. After antigen …

  Authors: Karin Reif, Eric H Ekland, Lars Ohl, Hideki Nakano, Martin Lipp, Reinhold Förster, Jason G Cyster

  Source: Nature. 2002 Mar 7

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• Trafficking on serpentines: molecular insight on how maturating T cells find their winding paths in the thymus.

  Maintenance of the peripheral T-cell pool throughout the life requires uninterrupted generation of T cells. The majority of peripheral T cells are gen…

  Authors: Ana Misslitz, Günter Bernhardt, Reinhold Förster

  Source: Immunological reviews. 2006 Feb

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