1 to 4 of 4 literature results

• Foxp3 transcription-factor-dependent and -independent regulation of the regulatory T cell transcriptional signature.

  The CD4(+)CD25(+) lineage of regulatory T (Treg) cells plays a key role in controlling immune and autoimmune responses and is characterized by a uniqu…

  Authors: Jonathan A Hill, Markus Feuerer, Kaley Tash, Sokol Haxhinasto, Jasmine Perez, Rachel Melamed, Diane Mathis, Christophe Benoist

  Source: Immunity. 2007 Nov

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• Gene expression microarrays: glimpses of the immunological genome.

  Successful microarray experimentation can generate enormous amounts of data, potentially very rich but also very unwieldy. Bold outlooks and new metho…

  Authors: Gordon Hyatt, Rachel Melamed, Richard Park, Reuben Seguritan, Catherine Laplace, Laurent Poirot, Silvia Zucchelli, Reinhard Obst, Michael Matos, Emily Venanzi,…

  Source: Nature immunology. 2006 Jul

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• The variable immunological self: genetic variation and nongenetic noise in Aire-regulated transcription.

  The Aire transcription factor plays an important role in immunological self-tolerance by mediating the ectopic expression of peripheral self-antigens …

  Authors: Emily S Venanzi, Rachel Melamed, Diane Mathis, Christophe Benoist

  Source: Proceedings of the National Academy of Sciences of the United States of America. 2008 Oct 14

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• Sustained antigen presentation can promote an immunogenic T cell response, like dendritic cell activation.

  Activation of dendritic cells (DCs) enhances their ability to prime naïve T cells. How activation renders them immunogenic rather than tolerogenic is …

  Authors: Reinhard Obst, Hisse-Martien van Santen, Rachel Melamed, Alice O Kamphorst, Christophe Benoist, Diane Mathis

  Source: Proceedings of the National Academy of Sciences of the United States of America. 2007 Sep 25

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