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1 to 10 of 14 literature results
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Functionally opposing roles of extracellular signal-regulated kinase 1/2 and p38 mitogen-activated protein kinase in the regulation of cardiac contractility.
BACKGROUND: Extracellular signal-regulated kinase 1/2 (ERK1/2) and p38 mitogen-activated protein kinase (p38-MAPK) have been shown to regulate various…
Authors: István Szokodi, Risto Kerkelä, Anna-Maria Kubin, Balázs Sármán, Sampsa Pikkarainen, Attila Kónyi, Iván G Horváth, Lajos Papp, Miklós Tóth, Réka Skoumal,…
Source: Circulation. 2008 Oct 14
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Diabetes mellitus attenuates the repolarization reserve in mammalian heart.
OBJECTIVE: In diabetes mellitus several cardiac electrophysiological parameters are known to be affected. In rodent experimental diabetes models chang…
Authors: Csaba Lengyel, László Virág, Tamás Bíró, Norbert Jost, János Magyar, Péter Biliczki, Erzsébet Kocsis, Réka Skoumal, Péter P Nánási, Miklós Tóth,…
Source: Cardiovascular research. 2007 Feb 1
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Evidence for a functional role of angiotensin II type 2 receptor in the cardiac hypertrophic process in vivo in the rat heart.
BACKGROUND: The precise function of angiotensin II type 2 receptor (AT2-R) in the mammalian heart in vivo is unknown. Here, we investigated the role o…
Authors: Zoltán Lakó-Futó, István Szokodi, Balázs Sármán, Gábor Földes, Heikki Tokola, Mika Ilves, Hanna Leskinen, Olli Vuolteenaho, Réka Skoumal, Rudolf deChâtel,…
Source: Circulation. 2003 Nov 11
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Prolactin-releasing peptide regulates cardiac contractility.
High levels of specific prolactin-releasing peptide (PrRP) binding sites have been found in the myocardium; however, the functional importance of PrRP…
Authors: Attila Kónyi, Réka Skoumal, Anna-Maria Kubin, Gábor Füredi, Abel Perjés, Klára Farkasfalvi, Zsolt Sárszegi, Ferenc Horkay, Iván G Horváth, Miklós Tóth,…
Source: Regulatory peptides. 2010 Jan 8
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Nuclear factor-kappaB signaling contributes to severe, but not moderate, angiotensin II-induced left ventricular remodeling.
OBJECTIVE: The transcription factor nuclear factor-kappaB (NF-kappaB) has been implicated in cardiomyocyte hypertrophy in vitro as well as in vivo; ho…
Authors: Balázs Sármán, Réka Skoumal, Hanna Leskinen, Jaana Rysä, Mika Ilves, Ylermi Soini, Juha Tuukkanen, Sampsa Pikkarainen, Zoltán Lakó-Futó, Beatrix Sármán,…
Source: Journal of hypertension. 2007 Sep
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Distinct modulation of angiotensin II-induced early left ventricular hypertrophic gene programming by dietary fat type.
Long-term dietary fatty acid intake alters the development of left ventricular hypertrophy, but the linking signaling pathways are unclear. We studied…
Authors: Gábor Földes, Szilvia Vajda, Zoltán Lakó-Futó, Balázs Sármán, Réka Skoumal, Mika Ilves, Rudolf deChâtel, István Karádi, Miklós Tóth, Heikki Ruskoaho,…
Source: Journal of lipid research. 2006 Jun
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A novel p38 MAPK target dyxin is rapidly induced by mechanical load in the heart.
Dyxin is a novel LIM domain protein acting as a transcriptional cofactor with GATA transcription factors. Here, we characterized dyxin as a p38 mitoge…
Authors: Hanne Luosujärvi, Jani Aro, Heikki Tokola, Hanna Leskinen, Olli Tenhunen, Réka Skoumal, István Szokodi, Heikki Ruskoaho, Jaana Rysä
Source: Blood pressure. 2010 Feb
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Involvement of endogenous ouabain-like compound in the cardiac hypertrophic process in vivo.
The Na(+)/K(+)-ATPase inhibitor ouabain has been shown to trigger hypertrophic growth of cultured cardiomyocytes; however, the significance of endogen…
Authors: Réka Skoumal, István Szokodi, Jani Aro, Gábor Földes, Mónika Göoz, Leila Seres, Balázs Sármán, Zoltán Lakó-Futó, Lajos Papp, Olli Vuolteenaho,…
Source: Life sciences. 2007 Mar 13
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N-terminal probrain natriuretic peptide level inversely correlates with cardiac index after arterial switch operation in neonates.
BACKGROUND: Natriuretic peptide levels are associated with cardiac output and ventricular function. We hypothesized that concomitant measurement of th…
Authors: Tamás Breuer, Erzsébet Sápi, Réka Skoumal, Miklós Tóth, Minna Ala-Kopsala, Olli Vuolteenaho, Juhani Leppäluoto, Heikki Ruskoaho, András Szatmári, Andrea Székely
Source: Paediatric anaesthesia. 2007 Aug
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Endothelin levels in experimental diabetes combined with cardiac hypertrophy.
Diabetes mellitus is associated with endothelial and cardiac dysfunction, and endothelin has been suggested to alter cardiac function by being a posit…
Authors: Réka Skoumal, Leila Seres, Pál Soós, Eva Balogh, Tìmea Kovàts, Jaana Rysa, Heikki Ruskoaho, Miklós Tóth, Ferenc Horkay
Source: Journal of cardiovascular pharmacology. 2004 Nov
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