1 to 10 of 48 literature results

• Glucolipotoxicity: fuel excess and beta-cell dysfunction.

  Glucotoxicity, lipotoxicity, and glucolipotoxicity are secondary phenomena that are proposed to play a role in all forms of type 2 diabetes. The under…

  Authors: Vincent Poitout, R Paul Robertson

  Source: Endocrine reviews. 2008 May

  View Free Full Text

• ATP-sensitive K+ channel mediates the zinc switch-off signal for glucagon response during glucose deprivation.

  OBJECTIVE: The intraislet insulin hypothesis proposes that glucagon secretion during hypoglycemia is triggered by a decrease in intraislet insulin sec…

  Authors: Michela Slucca, Jamie S Harmon, Elizabeth A Oseid, Joseph Bryan, R Paul Robertson

  Source: Diabetes. 2010 Jan

  View Full Text

• Estimation of beta-cell mass by metabolic tests: necessary, but how sufficient?

  This Perspectives in Diabetes addresses the accuracy of metabolic testing as a measure of pancreatic islet beta-cell mass in vivo in animals and in hu…

  Authors: R Paul Robertson

  Source: Diabetes. 2007 Oct

  View Full Text

• Editorial: Update on stem cell research.

  Authors: R Paul Robertson, Linda C Giudice

  Source: Endocrine reviews. 2009 May

  View Full Text

• Consequences on beta-cell function and reserve after long-term pancreas transplantation.

  beta-Cell replacement in diabetes using pancreatic islets or beta-cell surrogates is a research area undergoing intense scrutiny. Once this approach i…

  Authors: R Paul Robertson

  Source: Diabetes. 2004 Mar

  View Full Text

• Novel Nonimmunological Forms of {beta}-Cell Dysfunction: Diabetic Syndromes and Pathogenic Mechanisms.

  Authors: R Paul Robertson, Lydia Aguilar-Bryan

  Source: Endocrine reviews. 2008 May

  View Full Text

• ADA research funding in 2009: where will we be?

  Authors: R Paul Robertson

  Source: Diabetes. 2009 Jan

  View Full Text

• 2009 Presidential Address: mentoring ... touching the future.

  Authors: R Paul Robertson

  Source: Diabetes. 2009 Oct

  View Full Text

• Zinc, not insulin, regulates the rat alpha-cell response to hypoglycemia in vivo.

  The intra-islet insulin hypothesis proposes that the decrement in beta-cell insulin secretion during hypoglycemia provides an activation signal for al…

  Authors: Huarong Zhou, Tao Zhang, Jamie S Harmon, Joseph Bryan, R Paul Robertson

  Source: Diabetes. 2007 Apr

  View Full Text

• Intrahepatic glucose flux as a mechanism for defective intrahepatic islet alpha-cell response to hypoglycemia.

  OBJECTIVE: Glucagon responses to hypoglycemia from islets transplanted in the liver are defective. To determine whether this defect is related to intr…

  Authors: Huarong Zhou, Tao Zhang, Marika Bogdani, Elizabeth Oseid, Susan Parazzoli, Marie-Christine Vantyghem, Jamie Harmon, Michela Slucca, R Paul Robertson

  Source: Diabetes. 2008 Jun

  View Full Text